Interacting proteins: Q86US8 and Q92900 |
Pubmed |
SVM Score :0.0 |
Results indicate that hSmg5 / 7a functions in the dephosphorylation of Upf 1 . ^^^ Furthermore , hSmg5 / 7a copurifies with Upf 1 , Upf 2 , Upf3X , Smg 1 , and the catalytic subunit of protein phosphatase 2A . ^^^ These data indicate that hSmg5 / 7a targets protein phosphatase 2A to Upf 1 but not Upf 2 . ^^^ |
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Interacting proteins: Q86US8 and Q92900 |
Pubmed |
SVM Score :0.0 |
The proteins UPF 1 , SMG 5 , SMG 6 , and SMG 7 are essential NMD factors in metazoa . ^^^ When SMG 7 is tethered to a reporter transcript , it elicits its degradation , bypassing the requirement for a PTC , UPF 1 , SMG 5 , or SMG 6 . ^^^ |
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Interacting proteins: Q86US8 and Q92900 |
Pubmed |
SVM Score :0.0 |
UPF 1 is targeted for dephosphorylation by three related proteins , SMG 5 , SMG 6 , and SMG 7 . ^^^ |
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Interacting proteins: Q86US8 and Q92900 |
Pubmed |
SVM Score :0.0 |
We show that UPF 1 , UPF 2 , UPF 3 , SMG 1 , SMG 5 , and SMG 6 regulate in concert the expression of a cohort of genes with functions in a wide range of cellular activities , including cell cycle progression . ^^^ |
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Interacting proteins: Q86US8 and Q92900 |
Pubmed |
SVM Score :0.0 |
NA |
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