Interacting proteins: Q86UE8 and Q9UKI8 |
Pubmed |
SVM Score :0.0 |
DNA cloning and chromosomal mapping of genes encoding novel protein kinases termed PKU alpha and PKU beta , which have nuclear localization signal . ^^^ We have cloned cDNAs for novel serine / threonine protein kinases ( PK ) , termed PKU alpha and PKU beta , by screening a bacteriophage expression library for kinase activity . ^^^ Sequence analysis of PKU alpha and PKU beta genes revealed that their open reading frames ( ORF ) were 2151 and 2361 nucleotides ( nt ) encoding polypeptides of 717 and 787 amino acid ( aa ) residues , respectively . ^^^ The deduced aa sequences of PKU alpha and PKU beta contained typical serine / threonine PK domains at the C terminal region and were 86 % identical to each other , indicating that they belong to the same PK family . ^^^ The genes for PKU alpha and PKU beta were mapped to chromosome 17q23 and 8p12 p 22 , respectively , by fluorescence in situ hybridization . ^^^ |
|
Interacting proteins: Q86UE8 and Q9UKI8 |
Pubmed |
SVM Score :0.0 |
Here we report the cloning and characterization of two human putative homologues of the Arabidopsis TSL gene , termed TLK 1 and TLK 2 ( Tousled like kinase ) . ^^^ |
|
Interacting proteins: Q86UE8 and Q9UKI8 |
Pubmed |
SVM Score :0.0 |
In human cells , two structurally similar Tlks , Tlk 1 and Tlk 2 , were recently shown to be cell cycle regulated kinases with maximal activities during S phase . ^^^ |
|