| Interacting proteins: P25800 and Q86U70 |
Pubmed |
SVM Score :0.0 |
| LMO 1 , LMO 2 , and LMO 4 have distinct expression patterns in adult tissue , and we demonstrate that nuclear retention of LMO proteins is enhanced by the nuclear LIM interactor ( NLI ) . ^^^ |
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| Interacting proteins: P25800 and Q86U70 |
Pubmed |
SVM Score :0.0 |
| These characteristics imply that Ldb 1 Lmo4 interaction may function in the T cell developmental programme and that enforced expression of LMO 1 or LMO 2 by chromosomal translocations or transgenesis may displace Lmo 4 from this complex and thereby influence T cell differentiation prior to T cell tumour occurrence . . ^^^ |
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| Interacting proteins: P25800 and Q86U70 |
Pubmed |
SVM Score :0.0 |
| The LMO 1 and LDB 1 proteins interact in human T cell acute leukaemia with the chromosomal translocation t ( 11 ; 14 ) ( p 15 ; q 11 ) . ^^^ The latter is a phosphoprotein and binds to LMO 1 in its phosphorylated state and essentially all the LMO 1 and LDB 1 protein in the T cell line is part of the complex . ^^^ |
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| Interacting proteins: P25800 and Q86U70 |
Pubmed |
SVM Score :0.0 |
| The oncogenic functions of LMO 1 and LMO 2 are thought to be mediated by interaction with LDB 1 since they form a multimeric protein complex ( es ) . ^^^ |
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| Interacting proteins: P25800 and Q86U70 |
Pubmed |
SVM Score :0.0 |
| To gain information on the possible involvement of this transcription factor in the non responsiveness of acute myelocytic leukemia ( AML ) patients to ATRA , we compared the endogenous expression levels of Scl and its transcription complex partners [ i . e . , Rbtn 1 ( LMO 1 ) , Rbtn 2 ( LMO 2 ) , Ldb 1 , and GATA family proteins ] in leukemic blast cells from patients with AML and acute promyelocytic leukemia ( APL ) , and determined the effects of lithium chloride alone or in combination with ATRA on the capacity of blast cells to differentiate during short term ex vivo culture . ^^^ Levels of Scl , Rbtn 2 , GATA 1 , and Ldb 1 expression were comparable in AML and APL blasts , while the levels of expression of Rbtn 1 , GATA 2 , and GATA 3 were absent or markedly lower in APL cells . ^^^ |
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| Interacting proteins: P25800 and Q86U70 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P25800 and Q86U70 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P25800 and Q86U70 |
Pubmed |
SVM Score :0.0 |
| NA |
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