Interacting proteins: Q86U70 and P15923 |
Pubmed |
SVM Score :0.0 |
The composite motif binds a multi protein hematopoietic specific transcription factor complex which includes GATA 1 , SCL / tal 1 , E2A , Lmo 2 and Ldb 1 . ^^^ |
|
Interacting proteins: Q86U70 and P15923 |
Pubmed |
SVM Score :0.0 |
Human proerythroblasts and early erythroblasts , generated in vitro by normal adult progenitors , contain a pentamer protein complex comprising the tal 1 transcription factor heterodimerized with the ubiquitous E2A protein and linked to Lmo 2 , Ldb 1 , and retinoblastoma protein ( pRb ) . ^^^ |
|
Interacting proteins: Q86U70 and P15923 |
Pubmed |
SVM Score :0.0 |
This complex , containing hematopoietic specific ( SCL , Lim only 2 ( LMO 2 ) , GATA 1 / GATA 2 ) and ubiquitous ( E2A , LIM domain binding protein 1 [ Ldb 1 ] ) factors , is tethered to DNA via a specificity protein 1 ( Sp 1 ) motif , through direct interactions between elements of the SCL complex and the Sp 1 zinc finger protein . ^^^ |
|
Interacting proteins: Q86U70 and P15923 |
Pubmed |
SVM Score :0.0 |
In addition to known TAL 1 partners , GATA 1 , E2A , HEB , LMO 2 and Ldb 1 , we identify the ETO 2 repressor as a novel component recruited to TAL 1 complexes through interaction with E2A / HEB . ^^^ |
|
Interacting proteins: Q86U70 and P15923 |
Pubmed |
SVM Score :0.0 |
NA |
|