| A new rac target POSH is an SH 3 containing scaffold protein involved in the JNK and NF kappaB signalling pathways . ^^^ We have used yeast two hybrid selection and identified a new target of Rac , POSH . ^^^ We propose that POSH acts as a scaffold protein and contributes to Rac induced signal transduction pathways leading to diverse gene transcriptional changes . . ^^^ |