| Interacting proteins: Q6RW13 and P30556 |
Pubmed |
SVM Score :0.0 |
| Type 1 angiotensin 2 receptor associated protein ARAP 1 binds and recycles the receptor to the plasma membrane . ^^^ |
|
| Interacting proteins: Q6RW13 and P30556 |
Pubmed |
SVM Score :0.0 |
| Employing yeast two hybrid screening of a mouse kidney cDNA library with the carboxyl terminal cytoplasmic domain of the murine AT1a receptor as a bait , we have isolated a novel protein with a predicted molecular mass of 18 kDa , which we have named ATRAP ( for AT 1 receptor associated protein ) . ^^^ |
|
| Interacting proteins: Q6RW13 and P30556 |
Pubmed |
SVM Score :0.0 |
| ATRAP , novel AT 1 receptor associated protein , enhances internalization of AT 1 receptor and inhibits vascular smooth muscle cell growth . ^^^ We have identified a novel , membrane located protein that interacts specifically with the carboxyl terminal cytoplasmic domain of the AT1a receptor , which we named ATRAP ( for AT 1 receptor associated protein ) . ^^^ |
|
| Interacting proteins: Q6RW13 and P30556 |
Pubmed |
SVM Score :0.0 |
| A novel AT 1 receptor intracellular partner called AT 1 receptor associated protein ( ATRAP ) was identified , but its exact function has not been elucidated . ^^^ |
|
| Interacting proteins: Q6RW13 and P30556 |
Pubmed |
SVM Score :0.0 |
| We previously cloned a molecule that specifically bound to the AT 1 receptor and modulated AT 1 receptor signaling in vitro , which we named ATRAP ( for AT 1 receptor associated protein ) . ^^^ |
|
| Interacting proteins: Q6RW13 and P30556 |
Pubmed |
SVM Score :0.0 |
| Our group identified angiotensin 2 type 1 ( AT 1 ) receptor associated protein ( ATRAP ) in a yeast two hybrid screen for proteins that bind to the carboxyl terminal cytoplasmic domain of the AT 1 . ^^^ Mutant forms of ATRAP lacking the carboxyl end are unable to bind to the AT 1 receptor , leading to the formation of prominent perinuclear vesicle clusters . ^^^ Functional analysis of the effects of ATRAP on angiotensin 2 induced AT 1 receptor signaling reveals a moderate decrease in the generation of inositol lipids , a marked decrease in the angiotensin 2 stimulated transcriptional activity of the c fos promoter luciferase reporter gene , and a decrease in cell proliferation . . ^^^ |
|
| Interacting proteins: Q6RW13 and P30556 |
Pubmed |
SVM Score :0.0 |
| NA |
|