Pubmed abstracts for Protein-Protein Interaction search result :

Interacting proteins: Q6MZM7 and P18206	Pubmed	SVM Score :0.0
We also examined the distribution of F actin , alpha actinin , and vinculin in explanted fragments by immunocytochemical methods noting particularly their distribution with respect to FN lines . ^^^ Vinculin and alpha actinin in peripheral anchoring filopodia and lamellipodia co localized with the terminations of F actin bundles and with FN lines , suggesting that the peripheral cells were the moving force for explant translocation . ^^^
Interacting proteins: Q6MZM7 and P18206	Pubmed	SVM Score :0.0
The synthetic peptides ( Gly Arg Gly Asp [ GRGD ] and Gly Arg Gly Asp Ser Pro [ GRGDSP ] ) containing the tripeptide Arg Gly Asp ( RGD ) , originally found to be responsible for the cell binding activity of FN , have been found to inhibit EC spreading and the redistribution of their cytoskeleton , including the formation of stress fibers and the localization of vinculin either on fg or on FN . ^^^
Interacting proteins: Q6MZM7 and P18206	Pubmed	SVM Score :0.0
Immunofluorescent staining of MEC cultures with antibodies to the integrin beta 1 subunit demonstrated receptors on the basolateral surface at focal adhesion plaques that co localized with vinculin and with Fn positive matrix fibers . ^^^
Interacting proteins: Q6MZM7 and P18206	Pubmed	SVM Score :0.0
Both motile cell types also displayed relatively low numbers of focal contacts and microfilament bundles and limited amounts of localized vinculin , alpha actinin , and endogenous FN . ^^^
Interacting proteins: Q6MZM7 and P18206	Pubmed	SVM Score :0.0
We have recently observed a transmembrane association between extracellular fibronectin ( FN ) fibers and elongated focal patches or fibers of vinculin ( VN ) in G 1 arrested stationary Nil 8 hamster fibroblasts , with double label immunofluorescence microscopy ( Singer and Paradiso , 1981 , Cell . 24 : 481 492 ) . ^^^ We hypothesized that these FN VN complexes might correspond to focal contacts , the membrane sites that are probably mainly responsible for attaching cells to their substrata , because vinculin is often localized in focal contacts . ^^^ However , because fibronectin vinculin associations may not be restricted to the substrate adhesive surface of the cell , it became necessary to determine whether some or all of the various kinds of FN VN complexes which we described are in proximity to the substrate . ^^^ Using interference reflection optics and double label immunofluorescence microscopy for fibronectin and vinculin , many elongated ( up to 38 micrometer ) FN VN associations were found to be strikingly coincident with focal contacts in the perinuclear area of extremely flattened arrested Nil 8 fibroblasts in 0 . 3 % fetal bovine serum ( FBS ) . ^^^ Our time course experiments suggest that early FN VN lacking focal contacts , which form at the cellular margins , develop into mature substrate adhesion complexes containing both fibronectin and vinculin , localized in the major stress fibers at the centers of sessile fibroblasts . . ^^^
Interacting proteins: Q6MZM7 and P18206	Pubmed	SVM Score :0.0
Concomitantly , a dramatic clustering of alpha 5 beta 1 Fn receptors and of the focal contact associated proteins vinculin and talin occurred . ^^^
Interacting proteins: Q6MZM7 and P18206	Pubmed	SVM Score :0.0
Actin is one of the main protein components of the plate ; other proteins identified are a FN binding protein previously reported as a `` putative ' ' FN receptor the actin binding proteins myosin 2 , myosin 1 , alpha actinin , vinculin , and tropomyosin . ^^^
Interacting proteins: Q6MZM7 and P18206	Pubmed	SVM Score :0.0
Assembly of native FN induced a rapid reorganization of actin into stress fibers and colocalization of alpha 5 beta 1 integrin , focal adhesion kinase ( FAK ) , vinculin , and paxillin to regions of cell matrix contact . alpha 5 beta 1 integrins and FAK are also clustered upon binding of FN delta III 1 7 to cells but actin reorganization and focal adhesion formation are delayed and appear to be dependent on the formation of FN delta III 1 7 fibrils . ^^^
Interacting proteins: Q6MZM7 and P18206	Pubmed	SVM Score :0.0
Here , endothelial GM 7373 cells spread and organize focal adhesion plaques on immobilized FGF 2 , fibronectin ( FN ) , and vitronectin ( VN ) . alpha ( 5 ) beta ( 3 ) integrin , paxillin , focal adhesion kinase , vinculin and pp 60 ( src ) localize in cell substratum contact sites on FGF 2 , FN or VN . ^^^
Interacting proteins: Q6MZM7 and P18206	Pubmed	SVM Score :0.0
RPMC formed focal adhesions on FN in the presence of a regular glucose concentration ( 5 . 6 mmol / L ) ; however , tyrosine phosphorylation of FAK and p130Cas and formation of focal adhesions observed by FAK and vinculin staining were substantially inhibited by high glucose . ^^^
Interacting proteins: Q6MZM7 and P18206	Pubmed	SVM Score :0.0
Co immunoprecipitation experiments showed that a multimolecular signaling complex was formed by the amoebic FN receptor , FAK , paxillin , and vinculin . ^^^
Interacting proteins: Q6MZM7 and P18206	Pubmed	SVM Score :0.0
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Interacting proteins: Q6MZM7 and P18206	Pubmed	SVM Score :0.0
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Interacting proteins: Q6MZM7 and P18206	Pubmed	SVM Score :0.0
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Interacting proteins: Q6MZM7 and P18206	Pubmed	SVM Score :0.0
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Interacting proteins: Q6MZM7 and P18206	Pubmed	SVM Score :0.0
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Interacting proteins: Q6MZM7 and P18206	Pubmed	SVM Score :0.0
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Interacting proteins: Q6MZM7 and P18206	Pubmed	SVM Score :0.0
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Interacting proteins: Q6MZM7 and P18206	Pubmed	SVM Score :0.0
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Interacting proteins: Q6MZM7 and P18206	Pubmed	SVM Score :0.0
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Interacting proteins: Q6MZM7 and P18206	Pubmed	SVM Score :0.0
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Interacting proteins: Q6MZM7 and P18206	Pubmed	SVM Score :0.0
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Interacting proteins: Q6MZM7 and P18206	Pubmed	SVM Score :0.0
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Interacting proteins: Q6MZM7 and P18206	Pubmed	SVM Score :0.0
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Interacting proteins: Q6MZM7 and P18206	Pubmed	SVM Score :0.0
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Interacting proteins: Q6MZM7 and P18206	Pubmed	SVM Score :0.0
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Interacting proteins: Q6MZM7 and P18206	Pubmed	SVM Score :0.0
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