| Interacting proteins: Q16825 and P12931 |
Pubmed |
SVM Score :0.97123905 |
| In transient coexpression experiments PTPD 1 was found to be efficiently phosphorylated by and associated with the src kinase pp60src . . 0.97123905^^^ |
|
| Interacting proteins: Q16825 and P12931 |
Pubmed |
SVM Score :0.0 |
| PTP1C , a protein tyrosine phosphatase ( protein tyrosine phosphate phosphohydrolase , EC 3 . 1 . 3 . 48 ) containing two src homology 2 domains , is poorly active when assayed with various protein substrates in vitro . ^^^ |
|
| Interacting proteins: Q16825 and P12931 |
Pubmed |
SVM Score :0.0 |
| A protein tyrosine phosphatase ( PTPase ; EC 3 . 1 . 3 . 48 ) containing two Src homology 2 ( SH 2 ) domains , SHPTP 1 , was previously identified in hematopoietic and epithelial cells . ^^^ |
|
| Interacting proteins: Q16825 and P12931 |
Pubmed |
SVM Score :0.0 |
| We discovered a phosphotyrosine phosphatase ( PTPase ; EC 3 . 1 . 3 . 48 ) activity which associates with specific subcellular pools of c Src in vivo and which preferentially binds the SH 2 ( Src homology 2 ) domain of c Src in vitro . ^^^ |
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| Interacting proteins: Q16825 and P12931 |
Pubmed |
SVM Score :0.0 |
| Mitochondrial AKAP 121 binds and targets protein tyrosine phosphatase D 1 , a novel positive regulator of src signaling . ^^^ We find that AKAP121 / 84 also binds PTPD 1 , a src associated protein tyrosine phosphatase . ^^^ A signaling complex containing AKAP 121 , PKA , PTPD 1 , and src is assembled in vivo . ^^^ PTPD 1 activates src tyrosine kinase and increases the magnitude and duration of epidermal growth factor ( EGF ) signaling . ^^^ Expression of a PTPD 1 mutant lacking catalytic activity inhibits src and downregulates ERK 1 / 2 but does not affect the activity of c Jun N terminal kinase 1 / 2 and p38alpha mitogen activated protein kinase . ^^^ |
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| Interacting proteins: Q16825 and P12931 |
Pubmed |
SVM Score :0.0 |
| We find that AKAP 121 also targets src tyrosine kinase to mitochondria via PTPD 1 . ^^^ |
|
| Interacting proteins: Q16825 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q16825 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q16825 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|