| Interacting proteins: P00558 and Q16665 |
Pubmed |
SVM Score :0.0 |
| We have determined , by Northern analysis , the mRNA levels of HIF 1alpha and of two glycolytic enzymes known to be transcriptionally activated by HIF 1 , namely phosphoglycerate kinase 1 ( PGK 1 ) and pyruvate kinase M 2 ( PKM 2 ) , in different hepatoma cell lines and in mouse and human tissues . ^^^ |
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| Interacting proteins: P00558 and Q16665 |
Pubmed |
SVM Score :0.0 |
| The mRNA levels of several HIF 1alpha responsive genes , such as vascular endothelial growth factor ( VEGF ) , Glut 1 , and phosphoglycerate kinase 1 , increased in the Cited 2 ( / ) hearts . ^^^ |
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| Interacting proteins: P00558 and Q16665 |
Pubmed |
SVM Score :0.0 |
| We focused on genes important in vascular autonomic physiology , and / or activated by hypoxia ; hypoxia inducible factor 1 alpha ( HIF 1 alpha ) , 2 splicing variants of vascular endothelial growth factor ( VEGF ) ; VEGF 121 , VEGF 165 , and phosphoglycerate kinase 1 ( PGK 1 ) . ^^^ |
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| Interacting proteins: P00558 and Q16665 |
Pubmed |
SVM Score :0.0 |
| Neither HIF 1alpha , GLUT 1 , PGK 1 , nor VEGF mRNA was detectable in unwounded nontransgenic skin . ^^^ In epidermal carcinogenesis , HIF 1alpha , GLUT 1 , PGK 1 , and VEGF mRNAs were just detectable in early stage hyperplasia , markedly increased in high grade epidermal chest dysplasias , and further increased in invasive squamous carcinomas . ^^^ In neoplastic skin , HIF 1alpha , GLUT 1 , and PGK 1 mRNAs localized in the basal and immediate suprabasal epidermal layers , whereas VEGF mRNA was predominantly expressed in the more superior spinous and granular epidermal layers . ^^^ Immediately after wounding , HIF 1alpha , GLUT 1 , and PGK 1 mRNAs were detectable in basal keratinocytes at the wound edge . ^^^ |
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| Interacting proteins: P00558 and Q16665 |
Pubmed |
SVM Score :0.0 |
| In order to monitor HIF 1 transcriptional activity , we have developed HIF 1alpha responsive reporter constructs , in which lacZ gene expression is driven by minimal Hsp 70 gene promoter or minimal immediate early promoter of cytomegalovirus ( CMV ) and a combination of hypoxia response elements from regulatory regions of PGK 1 , ENO 1 and LDHA genes . ^^^ |
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| Interacting proteins: P00558 and Q16665 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00558 and Q16665 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00558 and Q16665 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00558 and Q16665 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00558 and Q16665 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00558 and Q16665 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00558 and Q16665 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00558 and Q16665 |
Pubmed |
SVM Score :0.0 |
| NA |
|