| Interacting proteins: Q07812 and Q16548 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q07812 and Q16548 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q07812 and Q16548 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q07812 and Q16548 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q07812 and Q16548 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q07812 and Q16548 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q07812 and Q16548 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q07812 and Q16548 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q07812 and Q16548 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q07812 and Q16548 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q07812 and Q16548 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q07812 and Q16548 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q07812 and Q16548 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q07812 and Q16548 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q07812 and Q16548 |
Pubmed |
SVM Score :1.1142738 |
| Structural basis of BFL 1 for its interaction with BAX and its anti apoptotic action in mammalian and yeast cells . 1.1142738^^^ We demonstrated in the yeast two hybrid system that BFL 1 interacts strongly with human BAX but is not able to form homodimers nor to interact with human BCL 2 or BCL xL . 0.95855005^^^ BAX requires the BH 3 domain for interaction with BFL 1 . 0.90716125^^^ However , the minimal region of BFL 1 for the interaction with BAX in coimmunoprecipitation experiments was not sufficient to protect cells from apoptosis . 0.87343613^^^ |
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| Interacting proteins: Q07812 and Q16548 |
Pubmed |
SVM Score :0.0 |
| We believe that the apoptosis of binucleate cells may be regulated by the balance of the BCL2A1 and BAX . ^^^ |
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| Interacting proteins: Q07812 and Q16548 |
Pubmed |
SVM Score :0.0 |
| In the yeast cell assay , BOD interacts with diverse antiapoptotic Bcl 2 proteins [ Mcl 1 , Bcl 2 , Bcl xL , Bcl w , Bfl 1 , and Epstein Barr virus ( EBV ) BHRF 1 ] but not with different proapoptotic Bcl 2 proteins ( BAD , Bak , Bok , and Bax ) . ^^^ |
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| Interacting proteins: Q07812 and Q16548 |
Pubmed |
SVM Score :0.0 |
| Mammary gland tissue , similar to many other tissues , expresses a number of different Bcl 2 relatives including bcl 10 , bax , bak , bad , bcl w , bfl 1 , bcl 2 as well as the bcl 2 binding protein Bag 1 . ^^^ |
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| Interacting proteins: Q07812 and Q16548 |
Pubmed |
SVM Score :0.0 |
| In the yeast two hybrid system , Mcl 1 binds to the hypophosphorylated mutant of BAD and interacts preferentially with different proapoptotic ( Bax , Bak , Bok , Bik , and BOD ) compared with antiapoptotic Bcl 2 family members ( Bcl 2 , Bcl xL , Bcl w , Bfl 1 , CED 9 , and BHRF 1 ) . ^^^ |
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| Interacting proteins: Q07812 and Q16548 |
Pubmed |
SVM Score :0.0 |
| Using reverse transcriptase polymerase chain reaction , cloning , and sequencing techniques , we have found that HL 60 cells express bak , bik , bax , bad , bcl 2 , bcl xL , bcl w , bfl 1 , fas , and caspases 1 4 and 7 10 . ^^^ Peripheral blood neutrophils expressed bak , bad , bcl w , bfl 1 , fas , and caspases 1 , 3 , 4 , and 7 10 , but hardly expressed bcl 2 , bcl xL , bik , bax , and caspase 2 . ^^^ |
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| Interacting proteins: Q07812 and Q16548 |
Pubmed |
SVM Score :0.0 |
| Adult mice exposed to greater than 95 % oxygen concentrations for 48 to 88 hours had increased whole lung mRNA levels of Bax and Bcl 10 ( L ) , no change in Bak , Bad , or Bcl 2 , and decreased levels of Bcl w and Bfl 1 . ^^^ Bax and Bfl 1 were not altered by hyperoxia in p 53 null mice ; however , oxygen toxicity was not lessened by p 53 deficiency . ^^^ |
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| Interacting proteins: Q07812 and Q16548 |
Pubmed |
SVM Score :0.0 |
| Bcl 2 family member Bfl 1 / A1 sequesters truncated bid to inhibit is collaboration with pro apoptotic Bak or Bax . ^^^ However , Bfl 1 remains tightly and selectively bound to tBid and blocks collaboration between tBid and Bax or Bak in the plane of the mitochondrial membrane , thereby preventing mitochondrial apoptotic activation . ^^^ Lack of demonstrable interaction between Bfl 1 and Bak or Bax in the mitochondrial membrane suggests that Bfl 1 generally prevents the formation of a pro apoptotic complex by sequestering BH 3 domain only proteins . . ^^^ |
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| Interacting proteins: Q07812 and Q16548 |
Pubmed |
SVM Score :0.0 |
| We observed down regulation of c Myc and of the anti apoptotic proteins Bcl 2 and Bfl 1 as well as high levels of the pro apoptotic proteins Bax and Bid . ^^^ Conversely , cells stably expressing NTD MR exhibited increased expression of Bcl 2 and Bfl 1 and diminished levels of Bid and Bax . ^^^ |
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| Interacting proteins: Q07812 and Q16548 |
Pubmed |
SVM Score :0.0 |
| The expression of apoptosis related genes BCL 2 , BAX , BCL2L1 , BCL2A1 , MCL 1 , DAPK 1 and MYC was studied by quantitative real time polymerase chain reaction on total RNA samples from patients with acute lymphoblastic leukaemia ( ALL , n = 16 ) , acute myeloid leukaemia ( AML , n = 27 ) , chronic myeloid leukaemia ( CML , n = 12 ) , mantle cell lymphoma ( MCL , n = 19 ) and chronic lymphoid leukaemia ( CLL , n = 32 ) . ^^^ BCL 2 , BAX , BCL2A1 , MCL 1 , DAPK 1 and MYC were overexpressed in all patient groups . ^^^ |
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| Interacting proteins: Q07812 and Q16548 |
Pubmed |
SVM Score :0.0 |
| The propensity of mitochondria to undergo permeability transition in the presence of a Ca2+ overload was determined along with distribution of various apoptotic regulators ( AIF , Smac 2 , Bax , cytochrome c , Bcl XL , Bfl 1 , and caspase 2 ) between mitochondria and cytoplasmic fractions . ^^^ |
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| Interacting proteins: Q07812 and Q16548 |
Pubmed |
SVM Score :0.0 |
| Spontaneous apoptosis of B CLL cells by in vitro culture resulted in decreased bcl 2 , bcl w , bfl 1 , mcl 1 , bak , bax , and bcl 2 / bax expression . ^^^ |
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| Interacting proteins: Q07812 and Q16548 |
Pubmed |
SVM Score :0.0 |
| In both cases , Oc survival was accompanied by analogous rises in the mRNA ratios for anti apoptotic Bcl xL and Bfl 1 relative to pro apoptotic Bax , and by marked protein suppression of the critical pro apoptotic signal Bim . ^^^ |
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| Interacting proteins: Q07812 and Q16548 |
Pubmed |
SVM Score :0.0 |
| Hepatic mRNA levels were measured for several pro apoptotic adaptors / regulators , including FasL , Fas receptor , FADD , TRADD , Bad , Bak , Bax , and Bcl 10 ( S ) , and anti apoptotic regulators , including Bcl w , Bcl 10 ( L ) , Bcl 2 , and Bfl 1 . ^^^ |
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