| Interacting proteins: Q16254 and P84022 |
Pubmed |
SVM Score :0.0 |
| Smad 3 and E2F 4 directly bound to the element ( TIE / E2F ) , and substitution of two nucleotides in TIE / E2F impaired binding of both Smad 3 and E2F 4 as well as serum induced activation and TGF beta induced suppression of the c myc promoter activity . ^^^ |
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| Interacting proteins: Q16254 and P84022 |
Pubmed |
SVM Score :0.0 |
| Recent work shows that c Myc repression by TGFbeta is mediated by the nuclear translocation of a novel , preformed complex composed of Smad 3 , E2F4 or E2F5 , and the Rb related factor p107 . . ^^^ |
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