| Interacting proteins: P08151 and Q15915 |
Pubmed |
SVM Score :0.0 |
| To clarify the mechanism of cerebellar development , we have cloned a gene , named zic , encoding a zinc finger protein that is expressed abundantly in granule cells throughout development of the cerebellum . zic has a significant homology to the zinc finger domain of the Caenorhabditis elegans tra 1 gene , the Drosophila cubitus interruptus Dominant gene , and the human GLI oncogene . ^^^ Furthermore , the bacterially expressed zic protein containing the zinc finger domains bound to the GLI binding sequence . ^^^ |
|
| Interacting proteins: P08151 and Q15915 |
Pubmed |
SVM Score :0.0 |
| Physical and functional interactions between Zic and Gli proteins . ^^^ Zic and Gli family proteins are transcription factors that share similar zinc finger domains . ^^^ Recent studies indicate that Zic and Gli collaborate in neural and skeletal development . ^^^ We provide evidence that the Zic and Gli proteins physically and functionally interact through their zinc finger domains . ^^^ Moreover , Gli proteins were translocated to cell nuclei by coexpressed Zic proteins , and both proteins regulated each other ' s transcriptional activity . ^^^ |
|
| Interacting proteins: P08151 and Q15915 |
Pubmed |
SVM Score :0.0 |
| A set of extracellular signals establishes the positional information in the ectoderm , which activates Prepattern genes ( Gli , Xiro , Zic , Dlx , etc . ) across extended and overlapping domains . ^^^ |
|
| Interacting proteins: P08151 and Q15915 |
Pubmed |
SVM Score :0.0 |
| The sequence of the zinc finger domain exhibits highest homology with those of members of the GLI and ZIC subfamilies of Krppel like proteins . ^^^ |
|
| Interacting proteins: P08151 and Q15915 |
Pubmed |
SVM Score :0.0 |
| Its five tandem Cys ( 2 ) His ( 2 ) zinc finger motifs exhibit the highest homology to those of members of the Gli and Zic subfamilies of Krppel like proteins . ^^^ |
|
| Interacting proteins: P08151 and Q15915 |
Pubmed |
SVM Score :0.0 |
| Its five tandem zinc finger motifs exhibit highest homology with those of members of the Gli and Zic subfamilies of Krppel like proteins . ^^^ |
|
| Interacting proteins: P08151 and Q15915 |
Pubmed |
SVM Score :0.0 |
| The vertebrate Zic gene family encodes C2H2 zinc finger transcription factors closely related to the Gli proteins . ^^^ |
|
| Interacting proteins: P08151 and Q15915 |
Pubmed |
SVM Score :0.0 |
| Recent molecular characterization has shown that Zic proteins are able to bind Gli binding DNA sequences in a sequence specific manner , but with lower affinity than Gli proteins . ^^^ Furthermore , Zic and Gli proteins interact physically via their zinc finger domains , raising the possibility that Zic proteins can act as transcriptional cofactors and modulate the hedgehog signaling pathway . ^^^ |
|
| Interacting proteins: P08151 and Q15915 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15915 and P08151 |
Pubmed |
SVM Score :0.0 |
| A set of extracellular signals establishes the positional information in the ectoderm , which activates Prepattern genes ( Gli , Xiro , Zic , Dlx , etc . ) across extended and overlapping domains . ^^^ |
|
| Interacting proteins: Q15915 and P08151 |
Pubmed |
SVM Score :0.0 |
| The sequence of the zinc finger domain exhibits highest homology with those of members of the GLI and ZIC subfamilies of Krppel like proteins . ^^^ |
|
| Interacting proteins: Q15915 and P08151 |
Pubmed |
SVM Score :0.0 |
| Its five tandem Cys ( 2 ) His ( 2 ) zinc finger motifs exhibit the highest homology to those of members of the Gli and Zic subfamilies of Krppel like proteins . ^^^ |
|
| Interacting proteins: Q15915 and P08151 |
Pubmed |
SVM Score :0.0 |
| Its five tandem zinc finger motifs exhibit highest homology with those of members of the Gli and Zic subfamilies of Krppel like proteins . ^^^ |
|
| Interacting proteins: Q15915 and P08151 |
Pubmed |
SVM Score :0.0 |
| The vertebrate Zic gene family encodes C2H2 zinc finger transcription factors closely related to the Gli proteins . ^^^ |
|
| Interacting proteins: Q15915 and P08151 |
Pubmed |
SVM Score :0.0 |
| Recent molecular characterization has shown that Zic proteins are able to bind Gli binding DNA sequences in a sequence specific manner , but with lower affinity than Gli proteins . ^^^ Furthermore , Zic and Gli proteins interact physically via their zinc finger domains , raising the possibility that Zic proteins can act as transcriptional cofactors and modulate the hedgehog signaling pathway . ^^^ |
|
| Interacting proteins: Q15915 and P08151 |
Pubmed |
SVM Score :0.0 |
| To clarify the mechanism of cerebellar development , we have cloned a gene , named zic , encoding a zinc finger protein that is expressed abundantly in granule cells throughout development of the cerebellum . zic has a significant homology to the zinc finger domain of the Caenorhabditis elegans tra 1 gene , the Drosophila cubitus interruptus Dominant gene , and the human GLI oncogene . ^^^ Furthermore , the bacterially expressed zic protein containing the zinc finger domains bound to the GLI binding sequence . ^^^ |
|
| Interacting proteins: Q15915 and P08151 |
Pubmed |
SVM Score :0.0 |
| Physical and functional interactions between Zic and Gli proteins . ^^^ Zic and Gli family proteins are transcription factors that share similar zinc finger domains . ^^^ Recent studies indicate that Zic and Gli collaborate in neural and skeletal development . ^^^ We provide evidence that the Zic and Gli proteins physically and functionally interact through their zinc finger domains . ^^^ Moreover , Gli proteins were translocated to cell nuclei by coexpressed Zic proteins , and both proteins regulated each other ' s transcriptional activity . ^^^ |
|
| Interacting proteins: Q15915 and P08151 |
Pubmed |
SVM Score :0.0 |
| NA |
|