| Interacting proteins: Q15831 and P04637 |
Pubmed |
SVM Score :0.0 |
| No evidence for linkage was found with markers near MSH 2 , MLH 1 , MCC , APC , HMPS , CDKN2A , JP 1 , PTEN , KRAS 2 , TP 53 , or LKB 1 . ^^^ |
|
| Interacting proteins: Q15831 and P04637 |
Pubmed |
SVM Score :0.0 |
| The past 15 years has seen the establishment of mouse lines heterozygous or homozygous null for genes known or suspected of being involved in human cancer syndromes , including APC , ATM , BLM , BRCA 1 , BRCA 2 , LKB 1 , MEN 1 , MLH , MSH , NF 1 , TP 53 , PTEN , RB 1 , TSC 1 , TSC 2 , VHL , and XPA . ^^^ |
|
| Interacting proteins: Q15831 and P04637 |
Pubmed |
SVM Score :0.0 |
| In this study , we used sequencing analysis to investigate the STK 11 , CDH 1 , and TP 53 loci for a germline mutation in two siblings with PJS with primary GC . ^^^ |
|
| Interacting proteins: Q15831 and P04637 |
Pubmed |
SVM Score :0.0 |
| METHODS : The involvement of STRAD in 42 PJS associated tumours ( sporadic lung , colon , gastric , and ovarian adenocarcinomas ) was studied using loss of heterozygosity ( LOH ) analysis of eight microsatellite markers on chromosome 17 , including TP 53 , BRCA 1 , and STRAD markers . ^^^ |
|
| Interacting proteins: Q15831 and P04637 |
Pubmed |
SVM Score :0.0 |
| Within the past few years , a number of genes associated with a high risk of breast cancer have been identified , including BRCA 1 , BRCA 2 , TP 53 , PTEN , MLH 1 , MSH 2 , and STK 11 . ^^^ |
|
| Interacting proteins: Q15831 and P04637 |
Pubmed |
SVM Score :0.0 |
| DNA was studied for loss of heterozygosity ( LOH ) at 19p ( STK 11 ) , 5q ( APC ) , and 17p ( TP 53 ) ; mutations in beta catenin , APC , and K RAS ; and microsatellite instability . ^^^ |
|