| Interacting proteins: Q15788 and Q92831 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15788 and Q92831 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15788 and Q92831 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15788 and Q92831 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15788 and Q92831 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15788 and Q92831 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15788 and Q92831 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15788 and Q92831 |
Pubmed |
SVM Score :0.0 |
| In addition , CBP associates with two other TSs , P / CAF and SRC 1 . ^^^ |
|
| Interacting proteins: Q15788 and Q92831 |
Pubmed |
SVM Score :0.0 |
| SRC 1 and PCAF ) . ^^^ |
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| Interacting proteins: Q15788 and Q92831 |
Pubmed |
SVM Score :0.0 |
| Overexpression of p 300 , SRC 1 or pCAF did not abrogate AP 1 suppression by RA , thus arguing against coactivator competition . ^^^ |
|
| Interacting proteins: Q15788 and Q92831 |
Pubmed |
SVM Score :0.0 |
| Here we show that SRC 1 possesses intrinsic histone acetyltransferase activity and that it also interacts with another HAT , p300 / CBP associated factor ( PCAF ) . ^^^ Acetylation by SRC 1 and PCAF of histones bound at specific promoters may result from ligand binding to steroid receptors and could be a mechanism by which the activation functions of steroid receptors and associated coactivators enhance formation of a stable preinitiation complex , thereby increasing transcription of specific genes from transcriptionally repressed chromatin templates . . ^^^ |
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| Interacting proteins: Q15788 and Q92831 |
Pubmed |
SVM Score :0.0 |
| The discovery that co activators such as Tetrahymena and yeast Gcn 5 , as well as human p300 / CBP , pCAF , Src 1 , ACTR and TAFII 250 , can acetylate histones suggests that activators may be involved in targeting acetylation activity to promoters . ^^^ |
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| Interacting proteins: Q15788 and Q92831 |
Pubmed |
SVM Score :0.0 |
| These subclasses include members of the steroid receptor coactivator 1 ( SRC 1 ) coactivator family , p300 / CBP and their associated proteins , such as p300 / CBP associated factor , human homologs of SWI / SNF proteins such as BRG 1 , and the less well characterized E 3 ubiquitin protein ligases E 6 papillomavirus protein associated protein and receptor potentiating factor 1 . ^^^ |
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| Interacting proteins: Q15788 and Q92831 |
Pubmed |
SVM Score :0.0 |
| To obtain some clue to these roles , we screened the expression levels of ER alpha , ER beta , coactivators ( SRC 1 , TIF 2 , AIB 1 , CBP , and P / CAF ) and corepressors ( N CoR and SMRT ) in 6 normal mammary glands , 6 intraductal carcinomas , 22 invasive ductal carcinomas , and 7 breast cancer cell lines using a multiplex reverse transcription PCR . ^^^ |
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| Interacting proteins: Q15788 and Q92831 |
Pubmed |
SVM Score :0.0 |
| In exploring the molecular mechanism involved in HNF 1 dependent gene activation in the in vivo chromatin context , we found that HNF 1 can physically interact with the histone acetyltransferases ( HATs ) CREB binding protein ( CBP ) , p300 / CBP associated factor ( P / CAF ) , Src 1 , and RAC 3 . ^^^ |
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| Interacting proteins: Q15788 and Q92831 |
Pubmed |
SVM Score :0.0 |
| Confirmed and putative HAT proteins have been identified from various organisms from yeast to humans , and they include Gcn 5 related N acetyltransferase ( GNAT ) superfamily members Gcn 5 , PCAF , Elp 3 , Hpa 2 , and Hat 1 : MYST proteins Sas 2 , Sas 3 , Esa 1 , MOF , Tip 60 , MOZ , MORF , and HBO 1 ; global coactivators p 300 and CREB binding protein ; nuclear receptor coactivators SRC 1 , ACTR , and TIF 2 ; TATA binding protein associated factor TAF ( 2 ) 250 and its homologs ; and subunits of RNA polymerase 3 general factor TFIIIC . ^^^ |
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| Interacting proteins: Q15788 and Q92831 |
Pubmed |
SVM Score :0.0 |
| Prominent in this diverse group is the steroid receptor coactivator 1 ( SRC 1 ) family , which interact with agonist bound nuclear receptors , thereby coupling them to multifunctional transcriptional coregulators such as CREB binding protein ( CBP ) , p 300 , and PCAF , all of which have potent histone acetyltransferase activity . ^^^ |
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| Interacting proteins: Q15788 and Q92831 |
Pubmed |
SVM Score :0.0 |
| The IL 8 promoter is regulated by NF kappaB / p65 in response to tumor necrosis factor alpha and requires the cooperation of the coactivators CBP / p300 and steroid receptor coactivator 1 ( SRC 1 ) and the p300 / CBP associated factor ( P / CAF ) for optimal activation . ^^^ |
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| Interacting proteins: Q15788 and Q92831 |
Pubmed |
SVM Score :0.0 |
| The absence of synergism by PCAF or DRIP 150 with SRC 1 or TIF 2 , respectively , further suggests that these other factors are not involved . ^^^ |
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| Interacting proteins: Q15788 and Q92831 |
Pubmed |
SVM Score :0.0 |
| We also show that the ligand dependent activities of ERalpha and progesterone receptor ( PR ) in yeast cells were strongly enhanced by the human p 160 protein steroid receptor coactivator ( SRC 1 ) , but not by CREB Binding Protein ( CBP ) or the p300 / CBP associated factor ( P / CAF ) . ^^^ |
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| Interacting proteins: Q15788 and Q92831 |
Pubmed |
SVM Score :0.0 |
| Here we show that the Bel1 / Tas mediated trans activation was enhanced by the coactivator p 300 , histone acetyltransferases PCAF and SRC 1 based on the crucial internal promoter BRE . ^^^ The potential mechanisms and functional roles of the three histone and factor acetyltransferases p 300 , PCAF , and SRC 1 in Bel1 / Tas mediated trans activation are discussed . . ^^^ |
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| Interacting proteins: Q15788 and Q92831 |
Pubmed |
SVM Score :0.0 |
| By contrast , the retinoid receptors associated transcriptional co factors , including the co repressors of N CoR and SMRT , and the co activators of SRC 1 and P / CAF , were ubiquitously expressed in the developing telencephalon . ^^^ |
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| Interacting proteins: Q15788 and Q92831 |
Pubmed |
SVM Score :0.0 |
| Chromatin immunoprecipitation analysis showed that E ( 2 ) induced recruitment of C / EBPbeta , ERalpha , SRC 1 , p 300 , pCAF , TFIIB , and Pol 2 , with no change in Sp1 / Sp3 . ^^^ |
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| Interacting proteins: Q15788 and Q92831 |
Pubmed |
SVM Score :0.0 |
| HPV 16 E7 has been previously reported to interact with p 300 and p300 / CBP associated factor ( PCAF ) , members of some SRC 1 transcriptional complexes . ^^^ We demonstrate here that HPV 16 E7 associates in vivo and in vitro with SRC 1 independently of p 300 and PCAF . ^^^ |
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