Interacting proteins: P55055 and Q15788 |
Pubmed |
SVM Score :0.0 |
YT 32 directly bound to LXRalpha and LXRbeta and induced the interaction of LXRalpha with cofactors , such as steroid receptor coactivator 1 , as effectively as the natural ligands , 22 ( R ) hydroxycholesterol and 24 ( S ) , 25 epoxycholesterol . ^^^ |
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Interacting proteins: P55055 and Q15788 |
Pubmed |
SVM Score :0.0 |
GSK 3987 recruits the steroid receptor coactivator 1 to human LXRalpha and LXRbeta with EC ( 50 ) s of 40 nM , profiles as an LXR agonist in functional assays , and activates LXR though a mechanism that is similar to first generation LXR agonists . . ^^^ |
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Interacting proteins: P55055 and Q15788 |
Pubmed |
SVM Score :0.0 |
Desmosterol bound to purified LXRalpha and LXRbeta in vitro and supported the recruitment of steroid receptor coactivator 1 . ^^^ |
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