| Interacting proteins: P43699 and Q15788 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: P43699 and Q15788 |
Pubmed |
SVM Score :0.9683795 |
| TTF 1 interacted with SRC 1 and CBP in vitro . 0.9683795^^^ |
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| Interacting proteins: P43699 and Q15788 |
Pubmed |
SVM Score :0.0 |
| Our laboratory has previously demonstrated that retinoic acid nuclear receptor , thyroid transcription factor 1 ( TTF 1 ) , and nuclear receptor coactivators such as cAMP response element binding protein ( CREB ) binding protein ( CBP ) / p300 and steroid receptor coactivator 1 ( SRC 1 ) form an enhanceosome on the 5 ' enhancer region of the human surfactant protein B gene . ^^^ |
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| Interacting proteins: P43699 and Q15788 |
Pubmed |
SVM Score :0.0 |
| In a second transgenic mouse line , an enhancer region , which binds to thyroid transcription factor 1 , retinoic acid receptor , signal transducers and activators of transcription 3 , and nuclear receptor coactivators ( SRC 1 , ACTR , TIF 2 , and CBP / p300 ) , was deleted from the hSP B 1 . 5 kb lacZ gene . ^^^ |
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| Interacting proteins: P43699 and Q15788 |
Pubmed |
SVM Score :0.0 |
| TTF 1 is acetylated by nuclear receptor coactivators including the activator of the thyroid and retinoic acid receptor , CREB binding protein , and steroid receptor coactivator 1 ( SRC 1 ) in cell transfection and immunoprecipitation studies . ^^^ A glutathionine transferase pull down assay shows TTF 1 direct interaction with the SRC 1 histone acetyltransferase domain . ^^^ |
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| Interacting proteins: P43699 and Q15788 |
Pubmed |
SVM Score :0.0 |
| The activity of TTF 1 is influenced by its interactions with other transcription factors and coactivators , including CBP / p300 and SRC 1 . ^^^ |
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| Interacting proteins: P43699 and Q15788 |
Pubmed |
SVM Score :0.0 |
| Using chromatin immunoprecipitation , we observed that when type 2 cells were cultured in 20 % O ( 2 ) , cAMP and IL 1 stimulated the recruitment of TTF 1 , p 65 , CBP , and steroid receptor coactivator 1 to the TBE region of the SP A promoter and increased local acetylation of histone H 3 ; these effects were prevented by hypoxia . ^^^ |
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