| Interacting proteins: Q15788 and P20226 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15788 and P20226 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15788 and P20226 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15788 and P20226 |
Pubmed |
SVM Score :1.0992592 |
| In vitro binding studies show that F SRC 1 binds to a variety of nuclear hormone receptors in a ligand dependent manner , along with TBP and TFIIB , suggesting that F SRC 1 may play a role as a bridging molecule between nuclear hormone receptors and general transcription factors . 1.0992592^^^ |
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| Interacting proteins: Q15788 and P20226 |
Pubmed |
SVM Score :0.67614248 |
| These results suggest that F SRC 1 can function via both CBP dependent and independent manners using various sets of activation domains and that direct interactions between F SRC 1 and TBP or TFIIB may not be important for CBP independent transcription . . 0.67614248^^^ |
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| Interacting proteins: Q15788 and P20226 |
Pubmed |
SVM Score :0.0 |
| We have analyzed several transcriptional steps that could be involved in the activation : the ability of these receptors 1 ) to interact with several coactivators ( steroid receptor coactivator 1 , SRC 1 ; transcription intermediary factor 1 , TIF 1 ; and estrogen receptor associated protein 140 , ERAP 140 ) and with members of the preinitiation complex [ TATA box binding protein ( TBP ) , transcription factor IIB ( TFIIB ) ] ; 2 ) to exhibit conformational changes revealed by proteolytic digest patterns similar to those observed for the wild type hormone occupied ER ; and 3 ) to bend estrogen response element containing DNA , which is thought to be one of the important phenomena triggering transcriptional activation . ^^^ |
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| Interacting proteins: Q15788 and P20226 |
Pubmed |
SVM Score :0.0 |
| Activating signal cointegrator 1 ( ASC 1 ) harbors an autonomous transactivation domain that contains a putative zinc finger motif which provides binding sites for basal transcription factors TBP and TFIIA , transcription integrators steroid receptor coactivator 1 ( SRC 1 ) and CBP p 300 , and nuclear receptors , as demonstrated by the glutathione S transferase pull down assays and the yeast two hybrid tests . ^^^ |
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| Interacting proteins: Q15788 and P20226 |
Pubmed |
SVM Score :0.0 |
| ASC 2 also interacted with other nuclear receptors , including retinoic acid receptor , thyroid hormone receptor , estrogen receptor alpha , and glucocorticoid receptor , basal factors TFIIA and TBP , and transcription integrators CBP / p300 and SRC 1 . ^^^ |
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