| Interacting proteins: P08235 and Q15788 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08235 and Q15788 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08235 and Q15788 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08235 and Q15788 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08235 and Q15788 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08235 and Q15788 |
Pubmed |
SVM Score :0.0 |
| Elevated levels of MR , the co activators TIF 2 and SRC 1 , and the co repressor SMRT do modulate the dose response curve and partial agonist activity of MR complexes . ^^^ |
|
| Interacting proteins: P08235 and Q15788 |
Pubmed |
SVM Score :0.0 |
| Here , we report a 1 . 95 A crystal structure of the MR ligand binding domain containing a single C808S mutation bound to corticosterone and the fourth LXXLL motif of steroid receptor coactivator 1 ( SRC 1 4 ) . ^^^ Through a combination of biochemical and structural analyses , we demonstrate that SRC 1 4 is the most potent MR binding motif and mutations that disrupt the MR / SRC1 4 interactions abolish the ability of the full length SRC 1 to coactivate MR . ^^^ |
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