| The zyxin related protein TRIP 6 interacts with PDZ motifs in the adaptor protein RIL and the protein tyrosine phosphatase PTP BL . ^^^ TRIP 6 also interacts with the second out of five PDZ motifs in PTP BL . ^^^ RNA expression analysis revealed overlapping patterns of expression for TRIP 6 , RIL and PTP BL , most notably in tissues of epithelial origin . ^^^ Furthermore , in transfected epithelial cells TRIP 6 can be co precipitated with RIL and PTP BL PDZ polypeptides , and a co localisation of TRIP 6 and RIL with Factin structures is evident . ^^^ Taken together , PTP BL , RIL and TRIP 6 may function as components of multi protein complexes at actin based sub cellular structures . . ^^^ |