| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.59494576 |
| The rel associated pp 40 protein prevents DNA binding of Rel and NF kappa B : relationship with 1 kappa B beta and regulation by phosphorylation . 0.59494576^^^ |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :1.0376095 |
| To address the importance of the association between rel and 1 kappa B proteins for oncogenesis by rel proteins , we characterized rel 1 kappa B interactions in chicken embryo fibroblasts ( CEF ) infected with retroviral vectors encoding the avian c rel ( p68c rel ) , 5 rel ( p59v rel ) , and 1 kappa B beta ( pp40I kappa B beta ) proteins . 1.0376095^^^ |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.77740864 |
| In resting naive cells c Rel is associated primarily with IkappaBbeta , an inhibitory molecule that is not effectively degraded by TCR signals . 0.77740864^^^ |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| Thus , expression of Tax in Jurkat T cells leads to the gradual depletion of IkappaBbeta , which is correlated with the induction of c Rel containing kappaB binding complexes . ^^^ Together , these studies suggest that Tax mediated inactivation Of IkappaBbeta may play a role in the persistent nuclear expression of c Rel induced by HTLV 1 infection . . ^^^ |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| Cultured fibroblasts derived from IkappaBalpha deficient embryos exhibit levels of NF kappaB 1 , NF kappaB 2 , RelA , c Rel , and IkappaBbeta similar to those of wild type fibroblasts . ^^^ |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| By contrast , selective inhibition of IkappaBbeta proteolysis by pretreatment of HepG 2 cells with the peptide aldehyde N acetyl Leu Leu norleucinal completely blocks the late phase of Rel A . ^^^ |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| CsA does not interfere with the synthesis of Rel proteins , but prevents the inducible degradation of cytosolic NF kappa B inhibitors 1 kappa B alpha and 1 kappa B beta upon T cell activation . ^^^ |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| The NF kappa B family members p 50 , p 65 , p 52 , c Rel , and RelB as well as the inhibitor proteins 1 kappa B alpha , 1 kappa B beta , and p 105 were present in uninjured arteries as determined by immunoblotting . ^^^ |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| In mammalian cells , 1 kappa B alpha and 1 kappa B beta proteins have been purified and shown to be the inhibitors of NF kappa B through their association with the p 65 or c Rel subunits . ^^^ |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| The reason for preferential nuclear translocation of RelA complexes appears to be selective inhibition by the 1 kappa B beta protein . 1 kappa B beta can efficiently inhibit p50 / RelA complexes , but has a much reduced ability to interfere with p50 / c Rel DNA binding both in vitro and in vivo . ^^^ |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| In vascular endothelial cells , 1 kappa B epsilon associates predominantly with the NF kappa B subunit Rel A and to a lesser extent with c Rel , whereas 1 kappa B alpha and 1 kappa B beta associate with Rel A only . ^^^ |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| We have applied these principles in order to form crystals of the Rel homology region of transcription factor NF kappaB in complex with its inhibitors IkappaBalpha and IkappaBbeta . ^^^ |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| Here we show that , unlike IkappaBalpha , IkappaBbeta and IkappaBepsilon appear to sequester p 65 or c Rel in the cytoplasm by inhibiting nuclear import . ^^^ |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| As inhibitory S ODN did not directly interfere with the NF kappaB DNA binding but prevented CpG induced NF kappaB nuclear translocation of p 50 , p 65 , and c Rel and blocked p 105 , IkappaBalpha , and IkappaBbeta degradation , we concluded that their putative target must lie upstream of inhibitory kinase ( IKK ) activation . . ^^^ |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| Decreased NF kappaB activation in non CD 28 costimulation resulted from the failure to translocate a critical NF kappaB member , c Rel , to the nuclear compartment due to the lack of IkappaBbeta inactivation . ^^^ |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| Cerulein induces NF kappaB / Rel via activation of IkappaB kinase ( IKK ) , which causes degradation of IkappaBalpha but not IkappaBbeta . ^^^ |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| Mitochondria to nucleus stress signaling : a distinctive mechanism of NFkappaB / Rel activation through calcineurin mediated inactivation of IkappaBbeta . ^^^ We demonstrate here that mitochondrial stress induced activation of NFkappaB / Rel factors involves inactivation of IkappaBbeta through Cn mediated dephosphorylation . ^^^ Chemical cross linking and coimmunoprecipitation show that NFkappaB / Rel factor bound IkappaBbeta forms a ternary complex with Cn under in vitro and in vivo conditions that was sensitive to FK 506 . ^^^ Mutations at S313 / S315 of IkappaBbeta abolished Cn binding , inhibited Cn mediated increase of Rel proteins in the nucleus , and had a dominant negative effect on the mitochondrial stress induced expression of RyR 1 and cathepsin L genes . ^^^ |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| Immunohistochemical evaluation included members of the NF kappaB ( p 50 , p 65 , p 52 , c Rel , Rel B ) and the IkappaB ( IkappaBalpha , IkappaBbeta , IkappaBepsilon , Bcl 3 ) families , as well as putative targets of NF kappaB such as Flip , Bcl xL , Cyclin D 1 , and oestrogen and progesterone receptors . ^^^ |
|
| Interacting proteins: Q15653 and Q04864 |
Pubmed |
SVM Score :0.0 |
| Whereas NFATc 1 expression was increased significantly at days 3 and 5 following RANK L exposure , there were no significant increases in the expression of NFkappaB subunits , namely p 65 , p 50 , c Rel , IkappaBalpha , and IkappaBbeta . ^^^ |
|