| Interacting proteins: Q15653 and Q04206 |
Pubmed |
SVM Score :0.0 |
| Cultured fibroblasts derived from IkappaBalpha deficient embryos exhibit levels of NF kappaB 1 , NF kappaB 2 , RelA , c Rel , and IkappaBbeta similar to those of wild type fibroblasts . ^^^ |
|
| Interacting proteins: Q15653 and Q04206 |
Pubmed |
SVM Score :0.0 |
| By contrast , selective inhibition of IkappaBbeta proteolysis by pretreatment of HepG 2 cells with the peptide aldehyde N acetyl Leu Leu norleucinal completely blocks the late phase of Rel A . ^^^ |
|
| Interacting proteins: Q15653 and Q04206 |
Pubmed |
SVM Score :0.0 |
| Unlike 1 kappa B alpha and 1 kappa B beta , 1 kappa B epsilon does not contain a C terminal PEST like sequence . 1 kappa B epsilon would , therefore , appear to regulate a late , transient activation of a subset of genes , regulated by RelA / cRel NF kappa B complexes , distinct from those regulated by other 1 kappa B proteins . . ^^^ |
|
| Interacting proteins: Q15653 and Q04206 |
Pubmed |
SVM Score :0.0 |
| The reason for preferential nuclear translocation of RelA complexes appears to be selective inhibition by the 1 kappa B beta protein . 1 kappa B beta can efficiently inhibit p50 / RelA complexes , but has a much reduced ability to interfere with p50 / c Rel DNA binding both in vitro and in vivo . ^^^ Consistent with these observations , 1 kappa B beta cotransfection can inhibit p50 / RelA mediated trans activation , but barely affects p50 / RelB mediated trans activation . . ^^^ |
|
| Interacting proteins: Q15653 and Q04206 |
Pubmed |
SVM Score :0.0 |
| A 549 cells expressed the IkappaB inhibitory subunits IkappaBalpha , IkappaBbeta , and p 105 ; however , following either stimulus , only the IkappaBalpha and IkappaBbeta steady state levels declined in parallel with the increase in RelA DNA binding activity . ^^^ |
|
| Interacting proteins: Q15653 and Q04206 |
Pubmed |
SVM Score :0.0 |
| Persistent activation of RelA by respiratory syncytial virus involves protein kinase C , underphosphorylated IkappaBbeta , and sequestration of protein phosphatase 2A by the viral phosphoprotein . ^^^ |
|
| Interacting proteins: Q15653 and Q04206 |
Pubmed |
SVM Score :0.0 |
| RESULTS : NF kappaB activation triggered by PMA was not associated with the disappearance of immunoreactive IkappaBalpha , IkappaBbeta , IkappaBgamma , or IkappaBepsilon or with the dissociation of intact IkappaB from RelA . ^^^ |
|
| Interacting proteins: Q15653 and Q04206 |
Pubmed |
SVM Score :0.0 |
| In vascular endothelial cells , 1 kappa B epsilon associates predominantly with the NF kappa B subunit Rel A and to a lesser extent with c Rel , whereas 1 kappa B alpha and 1 kappa B beta associate with Rel A only . ^^^ |
|
| Interacting proteins: Q15653 and Q04206 |
Pubmed |
SVM Score :0.0 |
| This is due to the Taxol mediated reactivation of RelA through phosphorylation and degradation of IkappaBbeta and the re expression of NF kappaB regulated bcl xl gene in these cancer cells as ectopic expression of the bcl xl gene confers resistance to Taxol induced apoptosis in PS 341 sensitized cells . ^^^ |
|
| Interacting proteins: Q15653 and Q04206 |
Pubmed |
SVM Score :0.0 |
| PS 341 treatment of these cells stabilized IkappaBalpha , IkappaBbeta , IkappaBvarepsilon , p 21 , p 27 and p 53 proteins and selectively inhibited Rel A DNA binding NF kappaB complexes . ^^^ |
|
| Interacting proteins: Q15653 and Q04206 |
Pubmed |
SVM Score :0.0 |
| Through the utilization of immunoprecipitation techniques , protein protein interactions between NF kappaB family members IkappaBalpha , IkappaBbeta , p 50 , and p 65 ( Rel A ) were identified with an Xpress tagged dominant negative c Jun ( TAM 67 ) protein . ^^^ |
|
| Interacting proteins: Q15653 and Q04206 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04206 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04206 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04206 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04206 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04206 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04206 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04206 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04206 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04206 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04206 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04206 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04206 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04206 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04206 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04206 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04206 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15653 and Q04206 |
Pubmed |
SVM Score :0.0 |
| NA |
|