| Interacting proteins: Q15653 and P38646 |
Pubmed |
SVM Score :0.0 |
| CsA does not interfere with the synthesis of Rel proteins , but prevents the inducible degradation of cytosolic NF kappa B inhibitors 1 kappa B alpha and 1 kappa B beta upon T cell activation . ^^^ These results indicate that CsA interferes with a specific event in the signal induced degradation of 1 kappa B alpha and 1 kappa B beta , but does not affect the processing of NF kappa B1 / p105 to p50 . . ^^^ |
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| Interacting proteins: Q15653 and P38646 |
Pubmed |
SVM Score :0.0 |
| CsA also inhibits both the prolonged , high rate of IkappaBalpha degradation and the lower level of IkappaBbeta turnover during the second phase of the activation response . ^^^ |
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