| Interacting proteins: P03973 and Q15653 |
Pubmed |
SVM Score :0.0 |
| Inhibition of NF kappaB activation and augmentation of IkappaBbeta by secretory leukocyte protease inhibitor during lung inflammation . ^^^ In the inflamed lungs , inhibition of NF kappaB activation by SLPI was associated with elevated levels of lung IkappaBbeta ( but not IkappaBalpha ) protein in the absence of elevated mRNA for IkappaBbeta . ^^^ When instilled into normal lung , SLPI also caused similar changes ( increases ) in lung IkappaBbeta . ^^^ |
|
| Interacting proteins: P03973 and Q15653 |
Pubmed |
SVM Score :0.0 |
| We have also demonstrated that SLPI prevents LPS induced interleukin 1 receptor associated kinase and IkappaBbeta degradation . ^^^ |
|
| Interacting proteins: P03973 and Q15653 |
Pubmed |
SVM Score :0.0 |
| IL 10 and IL 13 attenuate NF kappaB activation by interfering with breakdown of IkappaBalpha , while SLPI likewise suppresses NF kappaB activation , but by interfering with breakdown of IkappaBbeta . ^^^ |
|