| The serine / threonine kinase HIPK 2 interacts with TRADD , but not with CD 95 or TNF R 1 in 293T cells . ^^^ Here we describe that HIPK 2 can also associate with TRADD , a protein that interacts with tumor necrosis factor receptor type 1 ( TNF R 1 ) . ^^^ Under the conditions where HIPK2 / TRADD association was found , no direct interaction of HIPK 2 with CD 95 , TNF R 1 , FADD or caspase 8 could be detected . ^^^ |