| Interacting proteins: Q13490 and Q15628 |
Pubmed |
SVM Score :0.0 |
| The recruitment of TRAF 2 and c IAP 1 to TNF R 1 is TNF dependent , is mediated by TRADD , and is independent of TNF R 2 . ^^^ |
|
| Interacting proteins: Q13490 and Q15628 |
Pubmed |
SVM Score :0.0 |
| The first complex ( complex 1 ) is formed at the membrane by TNF R 1 , TRADD , RIP , TRAF 2 and c IAP 1 , while the second complex ( complex 2 ) , formed in the cytosol , predominantly contains FADD and pro caspases 8 / 10 but lacks TNF R 1 . ^^^ |
|
| Interacting proteins: Q13490 and Q15628 |
Pubmed |
SVM Score :0.0 |
| Members of this family can bind TRAF and TRADD molecules and activate NF kappaB and AP 1 , as can LMP 1 . ^^^ |
|
| Interacting proteins: Q13490 and Q15628 |
Pubmed |
SVM Score :0.0 |
| LMP 1 is targeted to the plasma membrane , where it binds TRAF , TRADD , and JAK molecules to activate NF kappaB , AP 1 , and STAT dependent pathways as does CD 40 . ^^^ |
|
| Interacting proteins: Q13490 and Q15628 |
Pubmed |
SVM Score :0.0 |
| The Latent Membrane Protein 1 of the Epstein Barr virus is required for human B lymphocyte immortalization and functions as a constitutively activated member of the TNF receptor family , through recruitment of TRAFs and TRADD molecules on its Carboxy terminal domain , leading to the activation of NF kappaB and AP 1 transcription factors . ^^^ |
|
| Interacting proteins: Q13490 and Q15628 |
Pubmed |
SVM Score :0.0 |
| In the normal rat cortex , a portion of TNFR 1 was present in lipid raft microdomains , where it associated with the adaptor proteins TRADD ( TNF receptor associated death domain ) , TNF receptor associated factor 2 ( TRAF 2 ) , the Ser / Thr kinase RIP ( receptor interacting protein ) , TRAF 1 , and cIAP 1 ( cellular inhibitor of apoptosis protein 1 ) , forming a survival signaling complex . ^^^ |
|
| Interacting proteins: Q13490 and Q15628 |
Pubmed |
SVM Score :0.0 |
| This was established by showing that CIN 85 was co precipitated with TNFR 1 , TRADD , cIAP 1 and TARF1 / 2 , but not with FADD , RIP , caspase 8 or TRAF 6 . ^^^ |
|
| Interacting proteins: Q13490 and Q15628 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q13490 and Q15628 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q13490 and Q15628 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q13490 and Q15628 |
Pubmed |
SVM Score :0.0 |
| NA |
|