| Interacting proteins: Q15485 and P48740 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q15485 and P48740 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15485 and P48740 |
Pubmed |
SVM Score :0.0 |
| In these studies , we defined a role of L ficolin / mannose binding lectin associated serine protease ( MASP ) complexes in Ca ( 2+ ) dependent , Ab independent opsonophagocytosis of serotype 3 GBS . ^^^ Incubation of GBS with affinity purified L ficolin / MASP complexes and C1q depleted serum deficient in CPS specific Ab supported opsonophagocytic killing , and this killing was inhibited by fluid phase N acetylglucosamine , the ligand for L ficolin . ^^^ We conclude that binding of L ficolin / MASP complexes to the CPS generates C 3 convertase C4b2a , which deposits C3b on GBS . ^^^ |
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| Interacting proteins: Q15485 and P48740 |
Pubmed |
SVM Score :0.0 |
| METHODS : To clarify the early phases of the complement activation cascade , we evaluated the deposition of initial proteins of the above two pathways ; IgG , IgM , mannose binding lectin ( MBL ) , H ficolin , L ficolin , MBL associated serine protease ( MASP ) 1 and MASP 2 in kidney allografts with PTC C4d deposition . ^^^ |
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