| Interacting proteins: Q15464 and P27986 |
Pubmed |
SVM Score :0.0 |
| The pro 4 / pro 5 motif of Shb binds in vitro particularly well to the Src , p 85 alpha PI 3 kinase and Eps 8 SH3 domains expressed as GST fusion proteins . ^^^ |
|
| Interacting proteins: Q15464 and P27986 |
Pubmed |
SVM Score :0.0 |
| Shb overexpression resulted also in the assembly and activation of a multiunit complex consisting of at least Shb , IRS 1 , IRS 2 , FAK , and PI3K . ^^^ Finally , Shb overexpression did not affect insulin induced phosphorylation of the PI3K antagonist PTEN . ^^^ CONCLUSION : It is concluded that the Shb induced alterations in the IRS 1 / PI3K / Akt pathway may be relevant to the understanding of growth and death patterns of insulin producing cells . . ^^^ |
|
| Interacting proteins: Q15464 and P27986 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15464 and P27986 |
Pubmed |
SVM Score :0.0 |
| NA |
|