Pubmed abstracts for Protein-Protein Interaction search result :


Interacting proteins: Q14151 and Q15424 Pubmed SVM Score :0.0
SAFB 2 , a new scaffold attachment factor homolog and estrogen receptor corepressor . ^^^ A search of the human genome for other potential SAFB family members revealed that KIAA 00138 ( now designated as SAFB 2 ) has high homology to SAFB ( now designated as SAFB 1 ) . ^^^ SAFB 1 and SAFB 2 are mapped adjacent to each other on chromosome 19p13 . 3 and are arranged in a bidirectional divergent configuration ( head to head ) , being separated by a short ( < 500 bp ) GC rich intergenic region that can function as a bidirectional promoter . ^^^ SAFB 1 and SAFB 2 share common functions but also have unique properties . ^^^ As shown previously for SAFB 1 , SAFB 2 functions as an estrogen receptor corepressor , and its overexpression results in inhibition of proliferation . ^^^
Interacting proteins: Q14151 and Q15424 Pubmed SVM Score :0.0
Scaffold attachment factors SAFB 1 and SAFB 2 : Innocent bystanders or critical players in breast tumorigenesis . ^^^ Scaffold attachment factor B 1 ( SAFB 1 ) and SAFB 2 are large , multifunctional proteins that have been implicated in numerous cellular processes including chromatin organization , transcriptional regulation , RNA splicing , and stress response . ^^^ For example , SAFB 2 can be found in both the nucleus and cytoplasm , whereas SAFB 1 seems to be mainly localized in the nucleus . ^^^ The possibility that SAFB 1 and SAFB 2 are novel breast tumor suppressor genes , and how they might function in this role , are discussed . . ^^^ Scaffold attachment factor B 1 ( SAFB 1 ) and SAFB 2 are large , multifunctional proteins that have been implicated in numerous cellular processes including chromatin organization , transcriptional regulation , RNA splicing , and stress response . ^^^
Interacting proteins: Q14151 and Q15424 Pubmed SVM Score :0.0
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