| Interacting proteins: Q9H307 and Q15287 |
Pubmed |
SVM Score :0.58470758 |
| Therefore , Pnn may participate , via its interaction with RNPS 1 , in mRNA metabolism in the nucleus , including mRNA splicing and export . . 0.58470758^^^ |
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| Interacting proteins: Q9H307 and Q15287 |
Pubmed |
SVM Score :0.0 |
| The N terminal region containing the serine rich ( S ) domain , the central RNA recognition motif ( RRM ) , and the C terminal arginine / serine / proline rich ( RS / P ) domain of RNPS 1 interact with p 54 , pinin , and hTra 2 beta , respectively . ^^^ |
|
| Interacting proteins: Q9H307 and Q15287 |
Pubmed |
SVM Score :0.0 |
| Regulation of 5 ( ' ) splice site choice was also observed for RNPS 1 , a general splicing activator that interacts with pnn in nuclear speckles . ^^^ The regulatory ability of pnn in alternative 5 ( ' ) splicing , however , was not dependent on RNPS 1 and a pnn mutant , lacking the N terminal 167 amino acids , behaved like a dominant negative species , inhibiting E1A splicing when applied in splicing assays . ^^^ |
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