| Interacting proteins: P15151 and Q15223 |
Pubmed |
SVM Score :0.0 |
| It furthermore showed Ca2+ independent heterophilic cell cell adhesion activity with Necl 2 / IGSF4 / RA175 / SgIGSF / TSLC1 / SynCAM1 from now on referred to as Necl 2 , nectin 1 and nectin 3 , but not with Necl 5 or nectin 2 . ^^^ |
|
| Interacting proteins: P15151 and Q15223 |
Pubmed |
SVM Score :0.0 |
| This membrane glycoprotein is poliovirus receptor related protein 1 ( Prr 1 ) , designated here as HveC . ^^^ Entry of alphaherpesviruses mediated by poliovirus receptor related protein 1 and poliovirus receptor . ^^^ |
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| Interacting proteins: P15151 and Q15223 |
Pubmed |
SVM Score :0.0 |
| HIgR shares its ectodomain with and appears to be an alternative splice variant of the previously described protein PRR 1 ( poliovirus receptor related protein ) . ^^^ Recently , PRR 1 , renamed HveC ( herpesvirus entry mediator C ) , and the related PRR 2 , renamed HveB , were reported to mediate the entry of HSV 1 , HSV 2 , and bovine herpesvirus 1 , and the homologous poliovirus receptor was reported to mediate the entry of pseudorabies virus ( R . ^^^ HIgR shares its ectodomain with and appears to be an alternative splice variant of the previously described protein PRR 1 ( poliovirus receptor related protein ) . ^^^ |
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| Interacting proteins: P15151 and Q15223 |
Pubmed |
SVM Score :0.0 |
| The full length cDNA of the murine homolog of human nectin1delta ( mNectin1delta ) , also known as human poliovirus receptor related 1 ( PRR 1 ) or herpesvirus entry mediator C , was cloned and showed a > 90 % identity with its human counterpart . mNectin1delta is expressed in some murine cell lines , exemplified by NIH 3T3 and L cells , and in murine tissues . ^^^ |
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| Interacting proteins: P15151 and Q15223 |
Pubmed |
SVM Score :0.0 |
| Chimeric nectin 1 poliovirus receptor molecules identify a nectin 1 region functional in herpes simplex virus entry . ^^^ |
|
| Interacting proteins: P15151 and Q15223 |
Pubmed |
SVM Score :0.0 |
| They belong to the immunoglobulin superfamily , are homologues of the poliovirus receptor ( PVR / CD155 ) , and were also named poliovirus receptor related ( PRR ) proteins . ^^^ |
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| Interacting proteins: P15151 and Q15223 |
Pubmed |
SVM Score :0.0 |
| This family comprises at least five members , namely nectin 1 , 2 , 3 , 4 , and poliovirus receptor ( PVR ) , that are involved in different physiological and pathological processes . ( 1 ) Nectins are adhesion molecules localized at adherens junctions in epithelial cells . ( 2 ) Some nectins act as poliovirus or alpha herpesvirus receptors ( nectin 1 ) . ( 3 ) Nectin 1 mutations are involved in orofacial developmental abnormalities in humans . ^^^ |
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| Interacting proteins: P15151 and Q15223 |
Pubmed |
SVM Score :0.0 |
| These include the identification of mutations in the interferon regulatory factor 6 ( IRF 6 ) gene as the cause of van der Woude syndrome and the poliovirus receptor related 1 ( PVRL 1 ) gene as being responsible for an autosomal recessive ectodermal dysplasia syndrome associated with clefting . ^^^ |
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| Interacting proteins: P15151 and Q15223 |
Pubmed |
SVM Score :0.0 |
| Here , we have identified the human poliovirus receptor related ( PRR ) family members CD 155 [ poliovirus receptor ( PVR ) ] and CD 112 ( nectin 2 / PRR 2 ) as the ligands for human CD 226 . ^^^ |
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| Interacting proteins: P15151 and Q15223 |
Pubmed |
SVM Score :0.0 |
| Three of them namely T box transcription factor 22 ( TBX 22 ) , poliovirus receptor like 1 ( PVRL 1 ) , and interferon regulatory factor 6 ( IRF 6 ) are responsible for causing 10 linked cleft palate , cleft lip / palate ectodermal dysplasia syndrome , and Van der Woude ' s and popliteal pterygium syndromes , respectively ; they are also implied in non syndromic cleft lip and palate . ^^^ |
|
| Interacting proteins: P15151 and Q15223 |
Pubmed |
SVM Score :0.0 |
| The aim of this study was to determine the sequence changes of the Cleft Lip and Palate Transmembrane Protein 1 ( CLPTM 1 ) and Poliovirus Receptor Related 1 ( PVRL 1 ) genes in patients with non syndromic complete clefts of lip , alveolus and palate and to correlate these findings with clinical features . ^^^ |
|
| Interacting proteins: P15151 and Q15223 |
Pubmed |
SVM Score :0.0 |
| The defects in plating efficiency and penetration could be corrected by expression of herpesvirus entry mediators B ( HveB ) , HveC , or HveD , with HveC being the most effective . ^^^ |
|
| Interacting proteins: P15151 and Q15223 |
Pubmed |
SVM Score :0.0 |
| We have isolated a human PVR related ( PRR ) cDNA . ^^^ The deduced amino acid ( aa ) sequence of PRR showed , in the extracellular region , 51 . 7 and 54 . 3 % similarity with human PVR and with the murine PVR homolog , respectively . ^^^ |
|
| Interacting proteins: P15151 and Q15223 |
Pubmed |
SVM Score :0.0 |
| To elucidate the molecular basis of this species specific infection of PV , we cloned orthologs of the PV receptor ( PVR ) gene ( pvr ) as well as those of PV receptor related genes 1 and 2 ( prr 1 and prr 2 ) from various mammalian species . ^^^ Comparison of the deduced amino acid sequences of PVR orthologs revealed that the NH ( 2 ) terminal immunoglobulin like domain ( domain 1 ) , which is the virus binding site in the human PVR , is highly variable among species , whereas that of PRR 1 is highly conserved . ^^^ |
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| Interacting proteins: P15151 and Q15223 |
Pubmed |
SVM Score :0.0 |
| We also carried out direct sequencing of the PVR and PVRL 2 candidate genes based on their homology to PVRL 1 , a gene shown previously to cause Margarita Island clefting . ^^^ |
|
| Interacting proteins: P15151 and Q15223 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15151 and Q15223 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15151 and Q15223 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15151 and Q15223 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15151 and Q15223 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15151 and Q15223 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15151 and Q15223 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15151 and Q15223 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15151 and Q15223 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15151 and Q15223 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15151 and Q15223 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15151 and Q15223 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15151 and Q15223 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15151 and Q15223 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15151 and Q15223 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15151 and Q15223 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15151 and Q15223 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15151 and Q15223 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15151 and Q15223 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15151 and Q15223 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15151 and Q15223 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15151 and Q15223 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15151 and Q15223 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15151 and Q15223 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15151 and Q15223 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15151 and Q15223 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15151 and Q15223 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15151 and Q15223 |
Pubmed |
SVM Score :0.0 |
| NA |
|