| Interacting proteins: Q14764 and P03372 |
Pubmed |
SVM Score :0.0 |
| The ESR spectra produced in irradiated dentin have been studied over a range of incident radiation energies from 50 kVp to 25 MVp . ^^^ |
|
| Interacting proteins: Q14764 and P03372 |
Pubmed |
SVM Score :0.0 |
| The amount of ER for one size of stent ( 3 . 0 mm ) was quantified using a 3D optical contactless machine ( Smartscope MVP , Rochester , NY ) . ^^^ |
|
| Interacting proteins: Q14764 and P03372 |
Pubmed |
SVM Score :0.0 |
| By immunoelectron microscopy , megalin and LRP were localized to clathrin coated pits at the cell surface in both undifferentiated and differentiated F 9 cells , whereas RAP was found mainly in the ER . ^^^ A sizeable pool of LRP was also detected in the ER . ^^^ |
|
| Interacting proteins: Q14764 and P03372 |
Pubmed |
SVM Score :0.0 |
| ERD 2 proteins mediate ER retention of the HNEL signal of LRP ' s receptor associated protein ( RAP ) . ^^^ Our recent studies have demonstrated that RAP is an endoplasmic reticulum ( ER ) resident protein and an intracellular chaperone for the LDL receptor related protein ( LRP ) . ^^^ |
|
| Interacting proteins: Q14764 and P03372 |
Pubmed |
SVM Score :0.0 |
| The 39 kDa receptor associated protein ( RAP ) is an endoplasmic reticulum ( ER ) resident protein , which is believed to function intracellularly as a molecular chaperone for LRP and to regulate its ligand binding activity along the secretory pathway . ^^^ |
|
| Interacting proteins: Q14764 and P03372 |
Pubmed |
SVM Score :0.0 |
| Specifically , we demonstrate that a MAb ( MAb 58K 9 ) preferentially interacts with the receptor associated protein ( RAP ) , a ubiquitous ER protein acting as a chaperone for the low density lipoprotein receptor related protein ( LRP ) in immunoprecipitation and immunoblotting analyses . ^^^ |
|
| Interacting proteins: Q14764 and P03372 |
Pubmed |
SVM Score :0.0 |
| LRP expression was independent of age of the patients , histology , tumor grade , estrogen receptor as well as progesterone receptor status , tumor size and lymph node involvement . ^^^ |
|
| Interacting proteins: Q14764 and P03372 |
Pubmed |
SVM Score :0.0 |
| The receptor associated protein ( RAP ) is a chaperone found primarily in the endoplasmic reticulum ( ER ) that plays a necessary role in the folding and exocytic trafficking of members of the LDL receptor gene family including megalin and the LDL receptor related protein ( LRP ) . ^^^ |
|
| Interacting proteins: Q14764 and P03372 |
Pubmed |
SVM Score :0.0 |
| The expression of LRP were positively correlated with the lymph nodes metastases ( r=0 . 197 , P < 0 . 05 ) and the expression of P gp ( r=0 . 179 , P < 0 . 05 ) and irrelative to age tumor size , histotype , lymph nodes metastases , tissue grading , clinical staging , and ER condition . ^^^ |
|
| Interacting proteins: Q14764 and P03372 |
Pubmed |
SVM Score :0.0 |
| A 104 kD protein was coimmunoprecipitated with the estrogen receptor from the flowtrough of a phosphocellulose chromatography of MCF 7 cell nuclear extract . mAbs to this protein identified several cDNA clones coding for the human 104 kD major vault protein . ^^^ The AER 317 antibody to estrogen receptor coimmunoprecipitated the major vault protein and the vault RNA also in the 20 , 000 g supernatant fraction . ^^^ Reconstitution experiments of estrogen receptor fragments with the major vault protein mapped the site of the interaction between amino acids 241 and 280 of human estrogen receptor , where the nuclear localization signal sequences are located . ^^^ Estradiol treatment of cells increased the amount of major vault protein present in the nuclear extract and coimmunoprecipitated with estrogen receptor , whereas the anti estrogen ICI 182 , 780 had no effect . ^^^ |
|
| Interacting proteins: Q14764 and P03372 |
Pubmed |
SVM Score :0.0 |
| To accommodate the intricate folding that such a complex structure dictates , a specialized chaperone is present in the endoplasmic reticulum ( ER ) called the receptor associated protein ( RAP ) that binds to LRP immediately following its biosynthesis and assists in its exocytic transport . ^^^ Such a tissue restricted effect by RAP prompted an investigation if other ER chaperones associate with LRP to assist in its complex folding requirements and compensate for the absence of RAP in RAP / cells . ^^^ In RAP / cells , three well known ER chaperones , calnexin , calreticulin , and protein disulfide isomerase ( PDI ) , associate with LRP and likely compensate for the absence of RAP . . ^^^ |
|
| Interacting proteins: Q14764 and P03372 |
Pubmed |
SVM Score :0.0 |
| RAP uses a histidine switch to regulate its interaction with LRP in the ER and Golgi . ^^^ |
|
| Interacting proteins: Q14764 and P03372 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14764 and P03372 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14764 and P03372 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14764 and P03372 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14764 and P03372 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14764 and P03372 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14764 and P03372 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14764 and P03372 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14764 and P03372 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14764 and P03372 |
Pubmed |
SVM Score :0.0 |
| NA |
|