| Interacting proteins: Q14566 and P25205 |
Pubmed |
SVM Score :0.0 |
| This gene family includes Saccharomyces cerevisiae MCM 2 , MCM 3 , MCM5 / CDC46 and CDC 47 , S . pombe nda 1 , nda 4 , cdc 21 and mis 5 , and genes encoding human BM 28 , P1MCM3 and P1 . 1MCM3 and mouse P1MCM3 , most of which are considered to be required for the initiation of DNA replication . ^^^ |
|
| Interacting proteins: Q14566 and P25205 |
Pubmed |
SVM Score :0.0 |
| BACKGROUND : The members of the MCM protein family , including MCM 2 , MCM 3 , Cdc 21 , CDC 46 , Mis 5 and CDC 47 , are considered to be involved in the control of a single round of DNA replication during S phase in eukaryotes . ^^^ |
|
| Interacting proteins: Q14566 and P25205 |
Pubmed |
SVM Score :0.0 |
| In addition , fractions of MCM 3 and MCM 6 proteins are released by nuclease digestion as monomeric proteins indicating that at least these two Mcm proteins may also occur as single molecules on chromatin . ^^^ |
|
| Interacting proteins: Q14566 and P25205 |
Pubmed |
SVM Score :0.0 |
| DNA cloning and expression during development of Drosophila melanogaster MCM 3 , MCM 6 and MCM 7 . cDNAs encoding three Drosophila melanogaster MCM proteins , DmMCM 3 , DmMCM 6 and DmMCM 7 , candidates of DNA replication licensing factors , were cloned and sequenced . ^^^ |
|
| Interacting proteins: Q14566 and P25205 |
Pubmed |
SVM Score :0.0 |
| Following exit from mitosis , the Mcm 4 subunit of the cytosolic interphase complex undergoes dephosphorylation , and the Mcm 2 , Mcm 3 , or Mcm 6 subunits are then actively phosphorylated by kinase ( s ) other than cyclin dependent kinases ( Cdks ) or Cdc 7 . ^^^ |
|
| Interacting proteins: Q14566 and P25205 |
Pubmed |
SVM Score :0.0 |
| Finally , using protein protein cross linking we have shown that MCM 2 interacts directly with MCM 5 and MCM 6 ; MCM 5 with MCM 3 and MCM 2 ; and MCM 6 with MCM 2 and MCM 4 . ^^^ |
|
| Interacting proteins: Q14566 and P25205 |
Pubmed |
SVM Score :0.0 |
| Twenty three of these genes were studied at the protein level ; expression of five ( MCM 4 , P = . 002 ; MCM 3 , P = . 030 ; MCM 6 , P = . 004 ; KPNA 2 , P = . 021 ; and geminin , P = . 004 ) was statistically significantly associated with overall survival in the validation set . ^^^ |
|
| Interacting proteins: Q14566 and P25205 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14566 and P25205 |
Pubmed |
SVM Score :0.0 |
| NA |
|