Pubmed abstracts for Protein-Protein Interaction search result :


Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.61669652
Sema3A binds with high affinity to neuropilin 1 on growth cone filopodial tips . 0.61669652^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.52549144
Sema3A , the vertebrate secreted semaphorin , binds to neuropilin 1 , which together with plexins constitutes the functional receptor . 0.52549144^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
Neuropilin ( neuropilin 1 ) was recently identified as a receptor for Collapsin 1 / Semaphorin III / D ( Sema 3 ) . ^^^ Unlike neuropilin 1 , which binds with high affinity to the three structurally related semaphorins Sema 3 , Sema E , and Sema 4 , neuropilin 2 shows high affinity binding only to Sema E and Sema 4 , not Sema 3 . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
The secreted semaphorins Sema 3 and Sema 4 and their receptors Neuropilin 1 and 2 are expressed in the hippocampal formation during appropriate stages . ^^^ An antibody against Neuropilin 1 blocks the repulsive action of Sema 3 and the entorhinal cortex , but has no effect on Sema 4 induced repulsion . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
To explore a role for chemorepulsive axon guidance mechanisms in the regeneration of primary olfactory axons , we examined the expression of the chemorepellent semaphorin 3 ( sema 3 ) , its receptor neuropilin 1 , and collapsin response mediator protein 2 ( CRMP 2 ) during regeneration of the olfactory system . ^^^ Sema 3 mRNA is expressed in pial sheet cells and in second order olfactory neurons that are the target cells of neuropilin 1 positive primary olfactory axons . ^^^ In contrast to the transient appearance of sema 3 positive cells at the lesion site after axotomy , sema 3 positive cells increase progressively after bulbectomy , apparently preventing regenerating neuropilin 1 positive nerve bundles from growing deeper into the lesion area . ^^^ The presence of sema 3 in scar tissue and the concomitant expression of its receptor neuropilin 1 on regenerating olfactory axons suggests that semaphorin mediated chemorepulsive signal transduction may contribute to the regenerative failure of these axons after bulbectomy . . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
Semaphorin 3 is a major component of this diffusible signal , and cortical neurons transduce this signal by way of the neuropilin 1 receptor . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
Role for semaphorin 3 and its receptor neuropilin 1 in neuronal regeneration and scar formation . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
Neuropilin 1 ( Npn 1 ) , a receptor for semaphorin 3 , mediates the guidance of growth cones on extending neurites . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
Two neuropilin 1 ligands , semaphorin 3 and VEGF 165 , can bind to these cells , and the addition of VEGF 165 to MS 5 cells increases expression of 2 cytokines known to regulate early hematopoiesis , Tpo and Flt 3 L . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
Neuropilin 1 , a neuronal cell surface semaphorin 3 receptor protein important for axonal guidance in developing peripheral nervous system efferents , has also been identified as a vascular endothelial growth factor ( VEGF ) receptor on endothelial cells . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
Plexin neuropilin 1 complexes form functional semaphorin 3A receptors . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
Neuropilin 1 is a receptor for Sema 3 . ^^^ The extracellular complement binding ( CUB ) and coagulation factor domains of neuropilin 2 confer specificity to the Sema 4 repulsive response , and these domains of neuropilin 1 are necessary and sufficient for binding of the Sema 3 semaphorin ( sema ) domain . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
Neuropilin 1 and neuropilin 2 show specificity in binding to different class 3 semaphorins , including Sema 3 , Sema E , and Sema 4 , suggesting that the specificity of action of these semaphorins is dictated by the complement of neuropilins expressed by responsive neurons . ^^^ In support of this , we show that sympathetic axons coexpress neuropilin 1 and 2 , that their responses to Sema 3 , Sema E , and Sema 4 are affected in predicted ways by antibodies to neuropilin 1 , and that neuropilin 1 and 2 can form homo and heterooligomers through an interaction involving at least partly the neuropilin MAM ( meprin , A 5 , mu ) domain . ^^^ These results support the idea that in sympathetic axons , the Sema 3 signal is mediated predominantly by neuropilin 1 oligomers , the Sema 4 signal by neuropilin 2 oligomers , and the Sema E signal by neuropilin 1 and 2 , either as homo or heterooligomers . . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
Neuropilin 1 , a sema 3 receptor , was expressed in injured neurons with projections to the lesion site , in a subpopulation of scar associated cells and in blood vessels around the scar . ^^^ The concomitant expression of sema 3 and its receptor neuropilin 1 in the scar suggests that sema III / neuropilin 1 mediated mechanisms are involved in CNS scar formation . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
Sema 3 A recombinant proteins inhibited migration of the wild type ( Nrp 1 expressing ) but not Nrp 1 deficient SG neurons in culture , suggesting that Nrp 1 mediated Sema3A inhibitory signals are essential in precise migration of SG neurons , as well as directional guidance of axons . . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
Expressions of neuropilin 1 , neuropilin 2 and semaphorin 3A mRNA in the rat brain after middle cerebral artery occlusion . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
Temporal regulation of neuropilin 1 expression and sensitivity to semaphorin 3A in NGF and NT 3 responsive chick sensory neurons . ^^^ This study compared the expression of the semaphorin 3A receptor subunit , neuropilin 1 , and the collapse response of growth cones to semaphorin 3A for NGF ( cutaneous ) and NT 3 ( proprioceptive ) dependent sensory axons extended from E 6 E10 chick embryos . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
Pontocerebellar axon guidance : neuropilin 1 and semaphorin 3A sensitivity gradients across basilar pontine nuclei and semaphorin 3A variation across cerebellum . ^^^ To assess the role of semaphorin 3A ( Sema3A ) and its receptor component neuropilin 1 ( Npn 1 ) in pontocerebellar axon guidance , we compared the distributions of Sema3A , Npn 1 , and DiI labeled pontocerebellar axons in neonatal mouse cerebellum . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
Cis and trans interactions of L 1 with neuropilin 1 control axonal responses to semaphorin 3A . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
Using coculture assays composed of tissues derived from the chick embryo or mutant mice treated with function blocking antibodies and phosphatidylinositol specific phospholipase C , we report here that the chemorepellent semaphorin 3A ( Sema3A ) and its receptor neuropilin 1 are required for mediating the dermamyotome and notochord derived , but not the ventral spinal cord derived , chemorepulsive signal for DRG axons . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
Semaphorin 3A ( Sema3A ) repels growing olfactory axons that express neuropilin 1 ( NP 1 ) , a receptor for Sema3A . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
The effects of one of these repulsive cues , semaphorin 3A ( Sema3A ) , are mediated by the membrane protein neuropilin 1 ( Npn 1 ) . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
Semaphorin 3A ( Sema3A ) is a membrane associated secreted protein that has chemorepulsive properties for neuropilin 1 ( npn 1 ) expressing axons . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
Specifically , LCG ( + ) axons preferentially grow into the region of the nerve layer that expresses high amounts of galectin 1 , beta 2 laminin , and semaphorin 3A , whereas neuropilin 1 ( + ) axons grow in a complementary pattern , avoiding the ventral nerve layer and projecting medially and laterally . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
The axon guidance signal semaphorin 3A induces the rapid collapse of growth cones by activating a receptor complex that contains neuropilin 1 as the ligand binding and a plexin as the signal transducing subunit . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
This review focuses on semaphorin 3A ( probably the best characterized semaphorin ) and its receptors ( in particular neuropilin 1 ) in the adult nervous system and argues that semaphorin 3A plays a role in the maintenance and regeneration of adult sensory neurons . . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
Neuropilin 1 ( NP 1 ) , in conjunction with plexins , promotes axon repulsion by binding to semaphorin 3A ( SEMA3A ) . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
Axon guidance molecules and related proteins such as semaphorin 3A , neuropilin 1 , plexin 1 , netrin 1 , growth associated protein , olfactory marker protein , cypin and collapsin response mediator proteins guide the development of neural circuits in the olfactory bulb . ^^^ The semaphorin 3A , neuropilin 1 , growth associated protein and collapsin response mediator protein 1 5 genes were expressed significantly higher during the early development stages than in adulthood while the opposite is true for the olfactory marker protein . ^^^ Sex differences of semaphorin 3A , neuropilin 1 as well as collapsin response mediator protein 3 at the early development stage and the late effect of neonatal testosterone propionate treatment on the expressions of netrin 1 , growth associated marker protein , cypin and collapsin response mediator proteins 1 , 3 and 5 genes may indicate a possible role of these molecules on sexual differentiation of the olfactory bulb . . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
Neuropilin 1 and Plexin A 1 are cell surface proteins that form a receptor complex for Semaphorin 3A ( Sema 3A ) , a secreted molecule mediating repelling signals for axonal growth cones . ^^^ We have analyzed the expression of Neuropilin 1 , Plexin A 1 , and Semaphorin 3A in the above mentioned tissues on the hypothesis that these molecules could regulate innervation in these organs during gestation . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
Semaphorin 3A can inhibit axonal growth and induce neuronal apoptosis following binding to neuropilin 1 , with the membrane proximal MAM ( meprin , A 5 , mu ) domain in neuropilin 1 playing a key role in the formation of a higher order receptor complex . ^^^ We have scored peptide pairs for complementary hydropathy and antisense homology to identify a candidate functional motif in the Ig domain of semaphorin 3A , and in the MAM domain of neuropilin 1 . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
These morphogenic effects of VEGF 165 require activation of both VEGF receptor 2 ( VEGFR 2 ) and neuropilin 1 ( Nrp 1 ) , since neutralizing antibodies to either of these receptors or the addition of semaphorin 3A ( which blocks VEGF 165 binding to Nrp 1 ) prevents the morphogenic response and the phosphorylation of VEGFR 2 along with the downstream signaling . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
We show that osteoblasts and chondrocytes differentiated in vitro express most members of the Semaphorin 3A signaling system ( Semaphorin 3A , Neuropilin 1 , and Plexins A 1 and A 2 ) . ^^^ Semaphorin 3A and Neuropilin 1 are also expressed in the bone marrow . ^^^ Expression patterns suggest Plexin A3 / Neuropilin 1 as a candidate receptor in target cells for the regulation of bone innervation by Semaphorin 3A . . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
Expression of mRNAs of Sema3A and neuropilin 1 ( NP 1 ) , a Sema3A receptor , was detected in fetal and adult lungs . ^^^ The fetal lung explants from neuropilin 1 homozygous null mice grew normally in vitro regardless of Sema3A treatment . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
Consistent with the insensitivity of trkC ( + ) collaterals to SEMA3A , these collaterals did not express neuropilin 1 , a receptor for SEMA3A . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
We detected the expression of netrin 1 and Sema3a in the optic chiasma , and that of Unc5h1 and neuropilin 1 in the optic nerve . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
Neuron restrictive silencer factor NRSF / REST is a transcriptional repressor of neuropilin 1 and diminishes the ability of semaphorin 3A to inhibit keratinocyte migration . ^^^ Neuropilin 1 ( NRP 1 ) is expressed by endothelial cells and neurons and serves as a receptor for both vascular endothelial growth factor ( VEGF ) , an angiogenesis factor , and semaphorin 3A ( Sema3A ) , a mediator of axonal guidance . ^^^ Neuropilin 1 ( NRP 1 ) is expressed by endothelial cells and neurons and serves as a receptor for both vascular endothelial growth factor ( VEGF ) , an angiogenesis factor , and semaphorin 3A ( Sema3A ) , a mediator of axonal guidance . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
Here , we show that Neuropilin 1 ( NRP 1 ) , the receptor for semaphorin 3A and VEGF A 165 and a member of the immune synapse , is also a physical and functional partner of HTLV 1 envelope ( Env ) proteins . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
Expression of neuropilin 1 , a component of the semaphorin 3A receptor , increased following injury . ^^^ CONCLUSIONS : We suggest that cell invasion , semaphorin 3A and neuropilin 1 induction , and disruption of the internal organization of the optic nerve contribute to axotomy induced degenerative processes . . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
Furthermore , the Sema3A receptor proteins , neuropilin 1 and plexin , and the Sema3A signaling molecule , rac 1 , also reorganize to vacuoles and membrane ridges after Sema3A treatment . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
Sema3A , a ligand for neuropilin 1 , is effective in repelling geniculate and trigeminal axons , and antineuropilin 1 , but not antineuropilin 2 , completely blocks the repulsion by arch explants that repel axon outgrowth from both ganglia . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
Neuropilin 1 ( NP 1 ) is a component of the receptor for semaphorin3a ( Sema3a ) , a member of a large family of molecules with widespread expression and demonstrable influence ( via their ability to repel growing axons ) on nervous system development . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
Oligodendrocytes were found to have Sema3A binding sites and to express neuropilin 1 , the major Sema3A receptor component . ^^^ In the presence of Sema3A , these oligodendrocytes displayed a dramatic reduction in process extension , which was reversed by removal of Sema3A and prevented by anti neuropilin 1 , anti Ulip6 / CRMP5 , anti Ulip2 / CRMP2 antibodies , or VEGF 165 , another neuropilin 1 ligand . ^^^ These results indicate the existence in the adult brain of a Sema3A signaling pathway that modulates oligodendrocyte process extension mediated by neuropilin 1 , Ulip6 / CRMP5 , and Ulip2 / CRMP2 , and they open new fields of investigation of neuron / oligodendrocyte interactions in the normal and pathological brain . . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
Requirement of neuropilin 1 mediated Sema3A signals in patterning of the sympathetic nervous system . ^^^ Neuropilin 1 is the specific receptor for Sema3A and plays a role in nerve fiber guidance . ^^^ We report that neuropilin 1 and Sema3A mutant mouse embryos , generated by targeted gene disruption , showed displacement of sympathetic neurons and their precursors and abnormal morphogenesis in the sympathetic trunk . ^^^ We also show that Sema3A suppressed the cell migration activity of sympathetic neurons from wild type but not neuropilin 1 mutant embryos in vitro and instead promoted their accumulation into compact cell masses and fasciculation of their neurites . ^^^ These findings suggest that the neuropilin 1 mediated Sema3A signals regulate arrest and aggregation of sympathetic neuron precursors and sympathetic neurons themselves at defined target sites and axon fasciculation to produce the stereotyped sympathetic nerve pattern . . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
This neurotrophin mediated decrease in the collapse response of DRG growth cones was not associated with reduced expression on growth cones of the Sema3A binding protein neuropilin 1 . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
Neuropilin 1 and plexin As form receptor complexes for Sema3A and plexin As are thought to initiate the intracellular signaling cascade . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
COS 7 cells coexpressing plexin A 4 with neuropilin 1 were induced to contract by Sema3A , a member of the class 3 semaphorin . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
After the initial discovery of neuropilin 1 as an epitope on axons recognized by a monoclonal antibody , neuropilins were rediscovered in the search for receptors mediating the repulsive actions of class 3 Semaphorins , notably Sema3A . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
VEGF 165 and Sema3A are competitive inhibitors for NRP 1 mediated functions in EC and neurons . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
Second , L 1 and NRP 1 , the neuropilin responsible for Sema3A binding , associate through their extracellular domains , forming a cell surface heterocomplex . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
Expression of sema3a1 in somites and neuropilin 1 , which encodes for a component of the Sema3a receptor , in angioblasts suggested that Sema3a1 regulates the pathway of the dorsally migrating angioblasts . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
SM 216289 diminished the binding of Sema3A to its receptor neuropilin 1 in vitro , suggesting a direct interference of receptor ligand association . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
As a rapid assay for CRMP , we exploited a reconstituted Sema3A signaling system in COS 7 cells expressing the receptor components Neuropilin 1 and PlexinA 1 ( NP1 / PlexA1 ) . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
This collapsing activity is partially blocked by neuropilin 1 antibodies and is absent in meningeal cells derived from Sema3A knockout mice . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
Following up on that initial observation , we have now used real time quantitative reverse transcription polymerase chain reaction to demonstrate induction of genes encoding neuropilin 1 ( NP 1 ) , which , like NP 2 , serves as a coreceptor for members of the class 3 semaphorin family of axonal guidance molecules and of five of the six known class 3 semaphorins ( Sema3A , Sema3B , Sema3C , Sema3E , and Sema3F , but not Sema3D ) in crushed or transected sciatic nerves . . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
Taking advantage of a collection of genetically engineered mouse mutants , we now demonstrate that the behavior of somata and axons of the facial nerve is regulated independently by two secreted ligands for the transmembrane receptor neuropilin 1 ( Nrp 1 ) , the semaphorin Sema3A and the VEGF 164 isoform of Vascular Endothelial Growth Factor . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
Interestingly , Schwann cell expression of mRNA encoding NRP 1 , which participates in Sema3A signaling , is not downregulated by forskolin . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
The class 3 Semaphorins Sema3A and Sema3F are potent axonal repellents that cause repulsion by binding Neuropilin 1 and Neuropilin 2 , respectively . ^^^ Sensory and sympathetic neurons from the double mutant are insensitive to Sema3A and Sema3F in vitro , and defects in axonal projections in vivo correspond to those seen in Neuropilin 1 and 2 mutants . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
The defects in peripheral sensory and SG axons were fundamentally related to those of neuropilin 1 or Sema3A mutant embryos reported but were more moderate than the phenotype in these mutants . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
GFP Sema3A exhibited a characteristic punctate distribution on the surface of Neuro 2a cells , localized to migratory pathways of cultured cells , and co localized with and induced clustering of its receptor component neuropilin 1 . ^^^ Heparin enhanced Sema3A ' s binding to neuropilin 1 expressing cells and potentiated its growth cone collapsing activity . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
Sema3A , a prototypical semaphorin , acts as a chemorepellent or a chemoattractant for axons by activating a receptor complex comprising neuropilin 1 as the ligand binding subunit and plexin A 1 as the signal transducing subunit . ^^^ Sema3A binding to neuropilin 1 induces the dissociation of FARP 2 from plexin A 1 , resulting in activation of FARP 2 ' s Rac GEF activity , Rnd 1 recruitment to plexin A 1 , and downregulation of R Ras . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
Using an in vivo model of microglia activation by striatal injection of lipopolysaccharide demonstrated a corresponding upregulation of Plexin A 1 and Neuropilin 1 in activated microglia and enhanced production of Sema3A by stressed adult neurons . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
This chapter describes the optimization of this assay and outlines the subtle differences required to enable Sema3A Fc and Sema4D Fc to induce identical collapse phenotypes in COS cells expressing Plexin A 1 and neuropilin 1 , or Plexin B 1 , respectively . . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
Neuropilin 1 ( NRP 1 ) , a receptor for Sema3A , is present on both axons and dendrites . ^^^ Neuropilin 1 ( NRP 1 ) , a receptor for Sema3A , is present on both axons and dendrites . ^^^ When the cultured neurons are exposed to Sema3A , the cluster size of PSD 95 is markedly enhanced , and an extensive colocalization of PSD 95 and NRP 1 or actin rich protrusion is seen . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
Vascular endothelial growth factor 165 ( VEGF 165 ) and semaphorin3A ( SEMA3A ) elicit pro and antiangiogenic signals respectively in endothelial cells ( ECs ) by binding to their receptors VEGFR 2 , neuropilin 1 ( NRP 1 ) , and plexin A 1 . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
In situ hybridization , imaging and biochemical techniques showed that the Sema3A receptor component neuropilin 1 is present at hippocampal synapses and localizes in the presynaptic membrane . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
Neuropilin 1 ( NP 1 ) has been identified as a necessary component of a semaphorin D ( SemD ) receptor that repulses dorsal root ganglion ( DRG ) axons during development . ^^^
Interacting proteins: Q14563 and O14786 Pubmed SVM Score :0.0
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