| Interacting proteins: Q14442 and Q9BRB3 |
Pubmed |
SVM Score :0.0 |
| The first step of the biosynthesis , the transfer of N acetylglucosamine from UDP N acetylglucosamine to phosphatidylinositol , is mediated by at least three genes in mammalian cells ( PIG A , PIG H and PIG C ) and in yeast ( GPI 1 , GPI 2 and GPI3 / SPT14 / CWH6 ) . ^^^ However , PIG H has no homology with GPI 1 or GPI 2 . ^^^ |
|
| Interacting proteins: Q14442 and Q9BRB3 |
Pubmed |
SVM Score :0.0 |
| The first step of glycosylphosphatidylinositol biosynthesis is mediated by a complex of PIG A , PIG H , PIG C and GPI 1 . ^^^ Mammalian PIG A and PIG C are homologous to yeast GPI 3 and GPI 2 , respectively ; however , mammalian PIG H is not homologous to yeast GPI 1 . ^^^ |
|
| Interacting proteins: Q14442 and Q9BRB3 |
Pubmed |
SVM Score :0.0 |
| In mammalian cells , this reaction is mediated by a complex of PIG A , PIG H , PIG C , and GPI 1 . ^^^ A lack of GPI 1 also caused partial decreases of PIG C and PIG H . ^^^ Therefore , GPI 1 stabilizes the enzyme by tying up PIG C with a complex of PIG A and PIG H . . ^^^ |
|
| Interacting proteins: Q14442 and Q9BRB3 |
Pubmed |
SVM Score :0.0 |
| The mammalian N acetylglucosaminyl transferase for the first step in glycosylphosphatidylinositol biosynthesis has been shown to consist of at least four components : PIG A , PIG C , PIG H and GPI 1 . ^^^ |
|
| Interacting proteins: Q14442 and Q9BRB3 |
Pubmed |
SVM Score :0.0 |
| GPI GnT is a uniquely complex glycosyltransferase , consisting of at least four proteins , PIG A , PIG H , PIG C and GPI 1 . ^^^ |
|
| Interacting proteins: Q14442 and Q9BRB3 |
Pubmed |
SVM Score :0.0 |
| This chemically simple step is genetically complex because three or four genes are required in both yeast ( GPI 1 , GPI 2 and GPI 3 ) and mammals ( GPI 1 , PIG A , PIG H and PIG C ) , respectively . ^^^ |
|
| Interacting proteins: Q14442 and Q9BRB3 |
Pubmed |
SVM Score :0.0 |
| The human enzyme has six known subunits , at least four of which , GPI 1 , PIG A , PIG C , and PIG H , have functional homologs in the budding yeast Saccharomyces cerevisiae . ^^^ |
|
| Interacting proteins: Q14442 and Q9BRB3 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9BRB3 and Q14442 |
Pubmed |
SVM Score :0.0 |
| The first step of the biosynthesis , the transfer of N acetylglucosamine from UDP N acetylglucosamine to phosphatidylinositol , is mediated by at least three genes in mammalian cells ( PIG A , PIG H and PIG C ) and in yeast ( GPI 1 , GPI 2 and GPI3 / SPT14 / CWH6 ) . ^^^ However , PIG H has no homology with GPI 1 or GPI 2 . ^^^ |
|
| Interacting proteins: Q9BRB3 and Q14442 |
Pubmed |
SVM Score :0.0 |
| The first step of glycosylphosphatidylinositol biosynthesis is mediated by a complex of PIG A , PIG H , PIG C and GPI 1 . ^^^ Mammalian PIG A and PIG C are homologous to yeast GPI 3 and GPI 2 , respectively ; however , mammalian PIG H is not homologous to yeast GPI 1 . ^^^ |
|
| Interacting proteins: Q9BRB3 and Q14442 |
Pubmed |
SVM Score :0.0 |
| In mammalian cells , this reaction is mediated by a complex of PIG A , PIG H , PIG C , and GPI 1 . ^^^ A lack of GPI 1 also caused partial decreases of PIG C and PIG H . ^^^ Therefore , GPI 1 stabilizes the enzyme by tying up PIG C with a complex of PIG A and PIG H . . ^^^ |
|
| Interacting proteins: Q9BRB3 and Q14442 |
Pubmed |
SVM Score :0.0 |
| The mammalian N acetylglucosaminyl transferase for the first step in glycosylphosphatidylinositol biosynthesis has been shown to consist of at least four components : PIG A , PIG C , PIG H and GPI 1 . ^^^ |
|
| Interacting proteins: Q9BRB3 and Q14442 |
Pubmed |
SVM Score :0.0 |
| GPI GnT is a uniquely complex glycosyltransferase , consisting of at least four proteins , PIG A , PIG H , PIG C and GPI 1 . ^^^ |
|
| Interacting proteins: Q9BRB3 and Q14442 |
Pubmed |
SVM Score :0.0 |
| This chemically simple step is genetically complex because three or four genes are required in both yeast ( GPI 1 , GPI 2 and GPI 3 ) and mammals ( GPI 1 , PIG A , PIG H and PIG C ) , respectively . ^^^ |
|
| Interacting proteins: Q9BRB3 and Q14442 |
Pubmed |
SVM Score :0.0 |
| The human enzyme has six known subunits , at least four of which , GPI 1 , PIG A , PIG C , and PIG H , have functional homologs in the budding yeast Saccharomyces cerevisiae . ^^^ |
|
| Interacting proteins: Q9BRB3 and Q14442 |
Pubmed |
SVM Score :0.0 |
| NA |
|