| Interacting proteins: P43351 and Q14191 |
Pubmed |
SVM Score :0.0 |
| WRN interacts physically and functionally with the recombination mediator protein RAD 52 . ^^^ Here we report a novel physical and functional interaction between WRN and the homologous recombination mediator protein RAD 52 . ^^^ Fluorescence resonance energy transfer ( FRET ) analyses show that WRN and RAD 52 form a complex in vivo that co localizes in foci associated with arrested replication forks . ^^^ Biochemical studies demonstrate that RAD 52 both inhibits and enhances WRN helicase activity in a DNA structure dependent manner , whereas WRN increases the efficiency of RAD 52 mediated strand annealing between non duplex DNA and homologous sequences contained within a double stranded plasmid . ^^^ These results suggest that coordinated WRN and RAD 52 activities are involved in replication fork rescue after DNA damage . . ^^^ |
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| Interacting proteins: P43351 and Q14191 |
Pubmed |
SVM Score :0.0 |
| To identify additional proteins required for the recruitment of BLM , we examined the recruitment of BLM in various mutants generated from chicken DT 40 cells and found that the early accumulation of BLM was not dependent on the presence of ATM , RAD 17 , DNA PKcs , NBS 1 , XRCC 3 , RAD 52 , RAD 54 , or WRN . ^^^ |
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| Interacting proteins: P43351 and Q14191 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43351 and Q14191 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43351 and Q14191 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43351 and Q14191 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43351 and Q14191 |
Pubmed |
SVM Score :0.0 |
| NA |
|