| Interacting proteins: Q14191 and P16104 |
Pubmed |
SVM Score :0.79794338 |
| WRN associates with H2AX in a manner dependent upon the M / R / N complex . 0.79794338^^^ Here , we show that WRN co localizes and associates with gamma H2AX , a marker protein of DNA double strand breaks ( DSBs ) , after cellular exposure to gamma irradiation . 0.53153429^^^ |
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| Interacting proteins: Q14191 and P16104 |
Pubmed |
SVM Score :0.0 |
| The accumulation of WRN at double strand breaks was rapid , persisted for many hours , and occurred in the absence of several known interacting proteins including polymerase beta , poly ( ADP ribose ) polymerase 1 ( PARP 1 ) , Ku 80 , DNA dependent protein kinase ( DNA PKcs ) , NBS 1 and histone H2AX . ^^^ |
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| Interacting proteins: Q14191 and P16104 |
Pubmed |
SVM Score :0.0 |
| The truncated WRN expressing cells also exhibited increased numbers of micronuclei , chromosome aberrations , and the foci of phosphorylated histone H2AX with 10 rays . ^^^ |
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