| Interacting proteins: O15372 and Q14152 |
Pubmed |
SVM Score :0.65645297 |
| Affinity purification of histidine tagged eIF3k from transiently transfected COS cells copurifies other eIF 3 subunits . eIF3k colocalizes with eIF 3 on 40S ribosomal subunits . eIF3k coexpressed with five other ' core ' eIF 3 subunits in baculovirus infected insect cells , forms a stable , immunoprecipitatable , complex with the ' core ' . eIF3k interacts directly with eIF3c , eIF3g and eIF3j by glutathione S transferase pull down assays . 0.65645297^^^ |
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| Interacting proteins: O15372 and Q14152 |
Pubmed |
SVM Score :0.0 |
| FLAG epitope tagged Tif 35 , a putative core eIF3g subunit , copurified with Int 6 and all five orthologs of core eIF 3 subunits . ^^^ |
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| Interacting proteins: O15372 and Q14152 |
Pubmed |
SVM Score :0.0 |
| We addressed the hypothesis that eIF 3 noncore subunits have accessory functions that help to regulate translation initiation , by focusing on the Arabidopsis thaliana eIF3h subunit . ^^^ Together , these data implicate eIF 3 in mRNA associated translation initiation events , such as scanning , start codon recognition , or reinitiation and suggest that poor translation initiation of specific mRNAs contributes to the pleiotropic spectrum of phenotypic defects in the eif3h mutant . . ^^^ |
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| Interacting proteins: O15372 and Q14152 |
Pubmed |
SVM Score :0.0 |
| Here we report the cloning and characterization of human cDNAs encoding the major RNA binding subunit , eIF 3 p66 , and two additional subunits , eIF 3 p47 and eIF 3 p40 . ^^^ The N terminal regions of human eIF 3 p40 and eIF 3 p47 are related to each other and to 17 other eukaryotic proteins , including murine Mov 34 , a subunit of the 26 S proteasome . ^^^ Phylogenetic analyses of the 19 related protein sequences , called the Mov 34 family , distinguish five major subgroups , where eIF 3 p40 , eIF 3 p47 , and Mov 34 are each found in a different subgroup . ^^^ |
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| Interacting proteins: O15372 and Q14152 |
Pubmed |
SVM Score :0.0 |
| High level amplification of eIF 3 p40 was found in 30 % of hormone refractory prostate tumors and in 18 % of untreated primary breast tumors . ^^^ The amplification of eIF 3 p40 gene was associated with overexpression of its mRNA , as expected for a functional target gene of the amplification . ^^^ These results imply that genomic aberrations of translation initiation factors , such as eIF 3 p40 , may contribute to the pathogenesis of breast and prostate cancer . . ^^^ |
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| Interacting proteins: O15372 and Q14152 |
Pubmed |
SVM Score :0.0 |
| The EIF3S3 gene encoding the p 40 subunit of the translation initiation factor eIF 3 has eight exons and maps to the Langer Giedion syndrome chromosome region on 8q24 , but is not the TRPS 1 gene . ^^^ We have mapped the gene encoding the p 40 subunit of the eukaryotic translation initiation factor eIF 3 ( EIF3S3 ) close to the distal border of the minimal critical region for tricho rhino phalangeal syndrome type 1 ( TRPS 1 ) on human chromosome 8q24 . ^^^ |
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| Interacting proteins: O15372 and Q14152 |
Pubmed |
SVM Score :0.0 |
| We have previously identified a putative target gene for the 8q gain , EIF3S3 , that encodes a p 40 subunit of eukaryotic translation initiation factor 3 ( eIF 3 ) . ^^^ |
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| Interacting proteins: O15372 and Q14152 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: O15372 and Q14152 |
Pubmed |
SVM Score :0.0 |
| NA |
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