| Interacting proteins: Q12815 and Q13895 |
Pubmed |
SVM Score :0.0 |
| A cytoplasmic protein , bystin , interacts with trophinin , tastin , and cytokeratin and may be involved in trophinin mediated cell adhesion between trophoblast and endometrial epithelial cells . ^^^ The present study identifies a cytoplasmic protein , named bystin , that directly binds trophinin and tastin . ^^^ Direct protein protein interactions of trophinin , tastin , and bystin analyzed by yeast two hybrid assays and by in vitro protein binding assays indicated that binding between bystin and trophinin and between bystin and tastin is enhanced when cytokeratin 8 and 18 are present as the third molecule . ^^^ Immunocytochemistry of bystin showed that bystin colocalizes with trophinin , tastin , and cytokeratins in a human trophoblastic teratocarcinoma cell , HT H . ^^^ |
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| Interacting proteins: Q12815 and Q13895 |
Pubmed |
SVM Score :0.0 |
| Expression of trophinin , tastin , and bystin by trophoblast and endometrial cells in human placenta . ^^^ Trophinin , tastin , and bystin comprise a complex mediating a unique homophilic cell adhesion between trophoblast and endometrial epithelial cells at their respective apical cell surfaces . ^^^ This analysis showed that trophoblast and endometrial epithelial cells at the utero placental interface express trophinin , tastin , and bystin . ^^^ In wk 10 placenta , trophinin and bystin were found in the intravillous cytotrophoblast , while tastin was not found in the villi . ^^^ |
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| Interacting proteins: Q12815 and Q13895 |
Pubmed |
SVM Score :0.0 |
| Bystin has been identified as a protein which mediates cellular interactions between trophoblastic and endometrial epithelial cells by forming complexes with two partners , trophinin and tastin , during embryo implantation . ^^^ |
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| Interacting proteins: Q12815 and Q13895 |
Pubmed |
SVM Score :0.0 |
| BACKGROUND : Bystin , Trophinin , and Tastin are component proteins of an adhesion molecule complex that plays a crucial role in the initial attachment of the embryo to the uterus . ^^^ |
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| Interacting proteins: Q12815 and Q13895 |
Pubmed |
SVM Score :0.0 |
| Trophinin , tastin , and bystin : a complex mediating unique attachment between trophoblastic and endometrial epithelial cells at their respective apical cell membranes . ^^^ Molecules involved in this unique cell adhesion were identified by expression complementary DNA cloning and were named trophinin , tastin , and bystin . ^^^ Tastin and bystin are cytoplasmic proteins required for trophinin to exhibit cell adhesion activity . ^^^ In human placenta , trophinin , tastin , and bystin are strongly expressed in trophoblast and endometrium at the uteroplacental interface at an early stage in pregnancy . ^^^ The unique expression pattern and cell adhesion activity exhibited by trophinin , tastin , and bystin suggest strongly the involvement of these molecules in the initial attachment of blastocyst to uterus . . ^^^ |
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| Interacting proteins: Q12815 and Q13895 |
Pubmed |
SVM Score :0.0 |
| Recent molecular approaches to elucidate the mechanism of embryo implantation : trophinin , bystin , and tastin as molecules involved in the initial attachment of blastocysts to the uterus in humans . ^^^ Instead of using human materials during the implantation period , two human tumor cell lines that respectively mimic the biological behaviors of a blastocyst and uterine luminal epithelial cells were utilized successfully to identify three novel adhesion molecules named trophinin , bystin , and tastin . ^^^ Bystin and tastin are cytoplasmic proteins that associate with trophinin by presumably forming an active adhesion machinery . ^^^ |
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| Interacting proteins: Q12815 and Q13895 |
Pubmed |
SVM Score :0.0 |
| Trophinin , tastin , and bystin have been identified as molecules potentially involved in human embryo implantation . ^^^ We hypothesized that trophinin ' s function in embryo implantation is unique to humans and investigated the expression of trophinin , tastin , and bystin in ectopic pregnancy , a condition unique to humans . ^^^ |
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