| Interacting proteins: P53667 and Q13873 |
Pubmed |
SVM Score :0.5103062 |
| Further analysis revealed that the interaction between LIMK 1 and BMPR 2 inhibited LIMK 1 ' s ability to phosphorylate cofilin , which could then be alleviated by addition of BMP 4 . 0.5103062^^^ |
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| Interacting proteins: P53667 and Q13873 |
Pubmed |
SVM Score :0.0 |
| Activation of LIMK 1 by binding to the BMP receptor , BMPRII , regulates BMP dependent dendritogenesis . ^^^ Here we show that LIM kinase 1 ( LIMK 1 ) , a key downstream effector of Rho GTPases , colocalizes with the BMP receptor , BMPRII , in the tips of neurites and binds to BMPRII . ^^^ Furthermore , we demonstrate that the physical interaction of LIMK 1 with BMPRII synergizes with the Rho GTPase , Cdc 42 , to activate LIMK 1 catalytic activity . ^^^ |
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| Interacting proteins: P53667 and Q13873 |
Pubmed |
SVM Score :0.0 |
| To access the system we screened a mutant of BMPR 2 where the interaction between BMPR 2 and LIMK is abrogated . ^^^ |
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