| Interacting proteins: Q13546 and Q9Y572 |
Pubmed |
SVM Score :0.53144618 |
| RIP 3 binds RIP through its unique C terminal segment and by virtue of this interaction is recruited to the tumor necrosis factor ( TNF ) receptor 1 signaling complex . 0.53144618^^^ |
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| Interacting proteins: Q13546 and Q9Y572 |
Pubmed |
SVM Score :0.0 |
| Mouse receptor interacting protein 3 does not contain a caspase recruiting or a death domain but induces apoptosis and activates NF kappaB . ^^^ Based upon domain organization and sequence similarity , this novel kinase , named mRIP 3 ( mouse receptor interacting protein 3 ) , appears to be a new RIP family member . ^^^ |
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| Interacting proteins: Q13546 and Q9Y572 |
Pubmed |
SVM Score :0.0 |
| ARIP 3 ( androgen receptor interacting protein 3 ) and other PIAS ( protein inhibitor of activated STAT ) proteins differ in their ability to modulate steroid receptor dependent transcriptional activation . ^^^ |
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| Interacting proteins: Q13546 and Q9Y572 |
Pubmed |
SVM Score :0.0 |
| Identification of a novel homotypic interaction motif required for the phosphorylation of receptor interacting protein ( RIP ) by RIP 3 . ^^^ |
|
| Interacting proteins: Q13546 and Q9Y572 |
Pubmed |
SVM Score :0.0 |
| Thyroid hormone receptor interacting protein 3 ( trip 3 ) is a novel coactivator of hepatocyte nuclear factor 4alpha . ^^^ In the present study , we showed , using a yeast two hybrid screening assay , that thyroid hormone receptor interacting protein 3 ( Trip 3 ) interacted with HNF 4alpha , and their interaction was confirmed by the glutathione S transferase pull down assay . ^^^ |
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| Interacting proteins: Q13546 and Q9Y572 |
Pubmed |
SVM Score :0.0 |
| Trif recruited the kinases receptor interacting protein ( RIP ) 1 and RIP 3 through its RIP homotypic interaction motif . ^^^ |
|
| Interacting proteins: Q13546 and Q9Y572 |
Pubmed |
SVM Score :0.0 |
| Nucleocytoplasmic shuttling of receptor interacting protein 3 ( RIP 3 ) : identification of novel nuclear export and import signals in RIP 3 . ^^^ Receptor interacting protein 3 ( RIP 3 ) , a member of the RIP Ser / Thr kinase family , has been characterized as a pro apoptotic protein involved in the tumor necrosis factor receptor 1 signaling pathway . ^^^ |
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| Interacting proteins: Q13546 and Q9Y572 |
Pubmed |
SVM Score :0.0 |
| RIP 3 beta and RIP 3 gamma , two novel splice variants of receptor interacting protein 3 ( RIP 3 ) , downregulate RIP 3 induced apoptosis . ^^^ Receptor interacting protein 3 ( RIP 3 ) is an apoptosis inducing member of the RIP family . ^^^ RIP 3 beta and RIP 3 gamma , two novel splice variants of receptor interacting protein 3 ( RIP 3 ) , downregulate RIP 3 induced apoptosis . ^^^ |
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| Interacting proteins: Q13546 and Q9Y572 |
Pubmed |
SVM Score :0.0 |
| RIP 3 ( receptor interacting protein 3 ) is a serine / threonine kinase that promotes apoptosis in various cell types . ^^^ RIP 3 ( receptor interacting protein 3 ) is a serine / threonine kinase that promotes apoptosis in various cell types . ^^^ |
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| Interacting proteins: Q13546 and Q9Y572 |
Pubmed |
SVM Score :0.0 |
| Identification of RIP 3 , a RIP like kinase that activates apoptosis and NFkappaB . ^^^ We isolated a kinase , RIP 3 , which shares homology with the kinase domain of RIP and RIP 2 ( also known as Rick or CARDIAK ) . ^^^ RIP 3 could be co immunoprecipitated with RIP , TRAF 2 and TNFR 1 in mammalian cells . ^^^ The carboxy terminal domain of RIP 3 , like that of RIP , could activate the transcription factor NFkappaB and induce apoptosis when expressed in mammalian cells . ^^^ As with RIP and RIP 2 , the kinase domain of RIP 3 was not required for either NFkappaB activation or apoptosis induction . ^^^ |
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| Interacting proteins: Q13546 and Q9Y572 |
Pubmed |
SVM Score :0.0 |
| The RIP like kinase , RIP 3 , induces apoptosis and NF kappaB nuclear translocation and localizes to mitochondria . ^^^ A RIP like protein , RIP 3 , has recently been reported that contains an N terminal kinase domain and a novel C terminal domain that promotes apoptosis . ^^^ These experiments further characterize RIP 3 mediated apoptosis and NF kappaB activation . ^^^ Northern blots indicate that rip 3 mRNA displays a restricted pattern of expression including regions of the adult central nervous system . ^^^ The rip 3 gene was localized by fluorescent in situ hybridization to human chromosome 14q11 . 2 , a region frequently altered in several types of neoplasia . ^^^ |
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| Interacting proteins: Q13546 and Q9Y572 |
Pubmed |
SVM Score :0.0 |
| Transfection of livin in HeLa cells resulted in protection from apoptosis induced by expression of FADD , Bax , RIP , RIP 3 , and DR 6 . ^^^ |
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| Interacting proteins: Q13546 and Q9Y572 |
Pubmed |
SVM Score :0.0 |
| RIP 1 and its homologs , RIP 2 and RIP 3 , form part of a family of Ser / Thr kinases that regulate signal transduction processes leading to NF kappa B activation . ^^^ |
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| Interacting proteins: Q13546 and Q9Y572 |
Pubmed |
SVM Score :0.0 |
| The characterization of a second maize RIP ( RIP 2 ) , encoded by the gene designated Rip 3 : 2 is described here . ^^^ Low levels of Rip 3 : 2 RNA were detected in roots , shoots , tassels , silks , and leaves , but the Rip 3 : 2 gene , unlike the Rip 3 : 1 gene , is not under the control of the transcriptional activator Opaque 2 . ^^^ Rip 3 : 2 encodes a 31 . 1 kDa polypeptide that is very similar to proRIP 1 in regions corresponding to those found in the active protein and the NH ( 2 ) terminal extension . ^^^ RIP activity assays revealed that Rip 3 : 2 encodes a polypeptide that acquires RNA specific N glycosidase activity after proteolytic cleavage . ^^^ |
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| Interacting proteins: Q13546 and Q9Y572 |
Pubmed |
SVM Score :0.0 |
| TRIF physically interacted with the RHIM containing proteins RIP 1 and RIP 3 , and deletion and mutational analyses revealed that the RHIM in TRIF was essential for TRIF induced apoptosis and contributed to TRIF induced NF kappa B activation . ^^^ |
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| Interacting proteins: Q13546 and Q9Y572 |
Pubmed |
SVM Score :0.0 |
| Rifampicin ( 1 ) was converted into four inactivated products by pathogenic Nocardia , RIP 1 and RIP 2 by N . brasiliensis and RIP 3 and RIP 4 by N . otitidiscaviarum . ^^^ |
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| Interacting proteins: Q13546 and Q9Y572 |
Pubmed |
SVM Score :0.0 |
| The kinase domain of PKK is similar to that of RIP , RIP 2 , and RIP 3 . ^^^ |
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| Interacting proteins: Q13546 and Q9Y572 |
Pubmed |
SVM Score :0.0 |
| Kinase RIP 3 is dispensable for normal NF kappa Bs , signaling by the B cell and T cell receptors , tumor necrosis factor receptor 1 , and Toll like receptors 2 and 4 . ^^^ RIP 3 is a member of the RIP kinase family . ^^^ Several studies have implicated RIP 3 in the regulation of apoptosis and NF kappa B signaling , but whether RIP 3 promotes or attenuates activation of the NF kappa B family of transcription factors has been controversial . ^^^ We have generated RIP 3 deficient mice by gene targeting and find RIP 3 to be dispensable for normal mouse development . ^^^ RIP 3 deficient cells showed normal sensitivity to a variety of apoptotic stimuli and were indistinguishable from wild type cells in their ability to activate NF kappa B signaling in response to the following : human tumor necrosis factor ( TNF ) , which selectively engages mouse TNF receptor 1 ; cross linking of the B or T cell antigen receptors ; peptidoglycan , which activates Toll like receptor 2 ; and lipopolysaccharide ( LPS ) , which stimulates Toll like receptor 4 . ^^^ |
|
| Interacting proteins: Q13546 and Q9Y572 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q13546 and Q9Y572 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q13546 and Q9Y572 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q13546 and Q9Y572 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q13546 and Q9Y572 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q13546 and Q9Y572 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q13546 and Q9Y572 |
Pubmed |
SVM Score :0.0 |
| NA |
|