| Interacting proteins: Q13546 and Q05397 |
Pubmed |
SVM Score :0.60118619 |
| Also , TNF induced association of FAK with RIP and subsequent association of RIP with TRAF 2 were not observed , resulting in a failure of RIP to recruit the IKK complex in FAK / cells . 0.60118619^^^ |
|
| Interacting proteins: Q13546 and Q05397 |
Pubmed |
SVM Score :0.0 |
| We have demonstrated that FAK binds to the death domain kinase receptor interacting protein ( RIP ) . ^^^ We have shown that RIP provides proapoptotic signals that are suppressed by its binding to FAK . ^^^ We thus propose that FAK overexpression in human tumors provides a survival signal function by binding to RIP and inhibiting its interaction with the death receptor complex . . ^^^ |
|
| Interacting proteins: Q13546 and Q05397 |
Pubmed |
SVM Score :0.0 |
| In HL 60 / FAK cells , the phosphoinositide 3 ( PI 3 ) kinase / Akt survival pathway was constitutively activated , accompanied by significant induction of inhibitor of apoptosis proteins , XIAP , RIP , and Bcl XL . ^^^ |
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