| Interacting proteins: O00220 and Q13546 |
Pubmed |
SVM Score :0.0 |
| The involvement of the death adaptor proteins FADD / MORT1 , TRADD , and RIP and the apoptosis initiating caspases 8 and 10 in death signaling by the two death inducing TRAIL receptors 1 and 2 ( TRAIL R 1 and TRAIL R 2 ) are controversial . ^^^ |
|
| Interacting proteins: O00220 and Q13546 |
Pubmed |
SVM Score :0.0 |
| The endogenous RIP protein was detected by immunoprecipitation in the TRAIL R 1 complex after TRAIL treatment . ^^^ |
|
| Interacting proteins: O00220 and Q13546 |
Pubmed |
SVM Score :0.0 |
| Rather , CARDINAL potently suppressed NF kappaB activation associated with overexpression of TRAIL R 1 , TRAIL R 2 , RIP , RICK , Bcl 10 , and TRADD , or through ligand induced stimulation of the interleukin 1 or tumor necrosis factor receptors . ^^^ |
|
| Interacting proteins: O00220 and Q13546 |
Pubmed |
SVM Score :0.0 |
| Thus , both DR 5 and DR 4 use FADD , TRADD , and RIP in their signal transduction pathways , and FADD is the common mediator of apoptosis by all known death domain containing receptors . . ^^^ |
|
| Interacting proteins: O00220 and Q13546 |
Pubmed |
SVM Score :0.0 |
| TRADD and RIP , which bound TNFR 1 , did not bind DR 4 and DR 5 . ^^^ |
|
| Interacting proteins: O00220 and Q13546 |
Pubmed |
SVM Score :0.0 |
| Substitution of the C terminal region of IKKgamma , which interacts with RIP , with a truncated DR 4 lacking its cytoplasmic death domain , produced a molecule that could induce IKK and NF kappaB activation in cells in response to TRAIL . ^^^ |
|
| Interacting proteins: O00220 and Q13546 |
Pubmed |
SVM Score :0.0 |
| Whereas exposure to 3 Cl AHPC results in NF kappaB activation , it inhibits the expression of XIAP , c IAP 1 , and Bcl 10 ( L ) and enhances the expression of proapoptotic molecules , including the death receptors DR 4 and DR 5 as well as Fas and Rip 1 . ^^^ |
|
| Interacting proteins: O00220 and Q13546 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00220 and Q13546 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00220 and Q13546 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00220 and Q13546 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00220 and Q13546 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00220 and Q13546 |
Pubmed |
SVM Score :0.0 |
| NA |
|