| Interacting proteins: Q9NR28 and Q13489 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q9NR28 and Q13489 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q9NR28 and Q13489 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q9NR28 and Q13489 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q9NR28 and Q13489 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q9NR28 and Q13489 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q9NR28 and Q13489 |
Pubmed |
SVM Score :0.0 |
| DIABLO ( direct IAP binding protein with low pI ) is a novel protein that can bind MIHA and can also interact with MIHB and MIHC and the baculoviral IAP , OpIAP . ^^^ DIABLO ( direct IAP binding protein with low pI ) is a novel protein that can bind MIHA and can also interact with MIHB and MIHC and the baculoviral IAP , OpIAP . ^^^ |
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| Interacting proteins: Q9NR28 and Q13489 |
Pubmed |
SVM Score :0.0 |
| Here we show that cIAP 1 and cIAP 2 are E 3 ubiquitin protein isopeptide ligases ( ubiquitin ligases ) for Smac . cIAPs stimulate Smac ubiquitination both in vivo and in vitro , leading to Smac degradation . cIAP 1 and cIAP 2 associate with overlapping but distinct subsets of E 2 ( ubiquitin carrier protein ) ubiquitin conjugating enzymes . ^^^ |
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| Interacting proteins: Q9NR28 and Q13489 |
Pubmed |
SVM Score :0.0 |
| As a result , three important regulators of apoptosis , Smac , HtrA 2 , and TRAF 2 , and three other proteins were identified as potential API 2 MALT1 binding proteins . ^^^ Immunoprecipitation analyses verified that API 2 MALT1 indeed binds to both exogeneous and endogeneous Smac proteins . ^^^ Furthermore , API 2 MALT1 significantly suppressed Smac promoted apoptosis in UV irradiated HeLa cells . ^^^ Thus , our results provide direct experimental evidence that API 2 MALT1 can confer resistance to apoptosis , at least in part , by neutralizing apoptosis promoted by Smac . . ^^^ |
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| Interacting proteins: Q9NR28 and Q13489 |
Pubmed |
SVM Score :0.0 |
| We recently provided direct evidence that API 2 MALT1 indeed exerts anti apoptotic action , in part , through its direct interaction with apoptotic regulators including Smac . ^^^ |
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| Interacting proteins: Q9NR28 and Q13489 |
Pubmed |
SVM Score :0.0 |
| In contrast , in MCF 7 lysates containing Smac and Omi / HtrA2 , active caspase 7 is released from the apoptosome and forms a stable approximately 200 kDa XIAP caspase 7 complex , which apparently does not contain cIAP 1 or cIAP 2 . ^^^ |
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| Interacting proteins: Q9NR28 and Q13489 |
Pubmed |
SVM Score :0.0 |
| We examined the expression profile of the caspases ( CASP 3 , 6 , 7 , 8 , 9 , 10 , and 14 ) , APAF 1 , SMAC , BCL 2 , the IAPs ( BIRC5 / survivin , CIAP 1 , CIAP 2 , XIAP , and LIVIN ) , and the proliferation markers Ki 67 and PHH 3 in 78 diffusely infiltrating astrocytomas and 24 normal brain samples by immunohistochemistry . ^^^ |
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