| Interacting proteins: P25942 and Q13489 |
Pubmed |
SVM Score :0.0 |
| In addition , SB 203580 selectively reduced CD 40 induced CD54 / ICAM 1 expression , whereas CD 40 dependent expression of CD 40 and CD95 / Fas and four newly defined CD 40 responsive genes cIAP 2 , TRAF 1 , TRAF4 / CART and DR 3 were unaffected . ^^^ |
|
| Interacting proteins: P25942 and Q13489 |
Pubmed |
SVM Score :0.0 |
| In addition , the transcription of c IAP 2 promoter was strongly up regulated when CD 40 or Epstein Barr virus latent membrane protein 1 was overexpressed . . ^^^ |
|
| Interacting proteins: P25942 and Q13489 |
Pubmed |
SVM Score :0.0 |
| Antisense knockdown of c iap 2 abolished CD 40 induced enhancement of eosinophil survival . ^^^ Sputum cells from asthmatic patients , unlike those from healthy subjects , substantially expressed CD 40 and c IAP 2 . ^^^ Moreover , a strong correlation was found between the percentage of eosinophils in the sputum from asthmatic patients and the sputum level of CD 40 and c IAP 2 expression . ^^^ CONCLUSION : The results demonstrate that CD 40 engagement enhances eosinophil survival through induction of c IAP 2 expression and suggest a role for this mechanism in allergic inflammation . . ^^^ |
|
| Interacting proteins: P25942 and Q13489 |
Pubmed |
SVM Score :0.0 |
| The inhibitor of apoptosis proteins cIAP 1 and cIAP 2 were also recruited by TRAF 2 to sites of CD 40 signaling . ^^^ |
|
| Interacting proteins: P25942 and Q13489 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P25942 and Q13489 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P25942 and Q13489 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P25942 and Q13489 |
Pubmed |
SVM Score :0.0 |
| NA |
|