Interacting proteins: Q13489 and P19438 |
Pubmed |
SVM Score :0.0 |
In the normal rat cortex , a portion of TNFR 1 was present in lipid raft microdomains , where it associated with the adaptor proteins TRADD ( TNF receptor associated death domain ) , TNF receptor associated factor 2 ( TRAF 2 ) , the Ser / Thr kinase RIP ( receptor interacting protein ) , TRAF 1 , and cIAP 1 ( cellular inhibitor of apoptosis protein 1 ) , forming a survival signaling complex . ^^^ |
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Interacting proteins: Q13489 and P19438 |
Pubmed |
SVM Score :0.0 |
TNFR 1 selective mutein decreased mRNA levels of aP 2 , a marker for adipogenic differentiation . ^^^ |
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Interacting proteins: Q13489 and P19438 |
Pubmed |
SVM Score :0.0 |
TNF RI and TNF RII signalling complexes also contain the anti apoptotic ( ' inhibitor of apoptosis ' ) molecules c IAP 1 and c IAP 2 ( refs 5 , 6 ) , which also have RING domain dependent ubiquitin protein ligase ( E 3 ) activity . ^^^ |
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Interacting proteins: Q13489 and P19438 |
Pubmed |
SVM Score :0.0 |
Here we show that AIP 1 is localized on the plasma membrane in resting endothelial cells ( EC ) in a complex with TNFR 1 . ^^^ TNF binding induces release of AIP 1 from TNFR 1 , resulting in cytoplasmic translocation and concomitant formation of an intracellular signaling complex comprised of TRADD , RIP 1 , TRAF 2 , and AIPl . ^^^ A proline rich region ( amino acids 796 807 ) is critical for maintaining AIP 1 in a closed form , which associates with a region of TNFR 1 distinct from the death domain , the site of TNFR 1 association with TRADD . ^^^ |
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Interacting proteins: Q13489 and P19438 |
Pubmed |
SVM Score :0.0 |
This report analyzes the gene expression of bcl xs , bcl xl , bax alpha , bax beta , fadd , fas , fas ligand ( fas L ) , ice , TNF alpha , TNF beta , TNFR 1 , TNFR 2 , TRAF 1 , TRAF 2 , TRAF 3 , cIAP 2 , and tradd at the level of mRNA in the single Reed Sternberg cells and their variants . ^^^ |
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Interacting proteins: Q13489 and P19438 |
Pubmed |
SVM Score :0.0 |
Tumor necrosis factor ( TNF ) receptor ( TNFR ) associated factors 1 and 2 ( TRAF 1 and TRAF 2 ) and inhibitor of apoptosis proteins cIAP 1 ( MIHB ) and cIAP 2 ( MIHC ) were recently identified as proteins that associate with the TNF alpha receptors TNFRI ( p 55 ) and TNFRII ( p 75 ) and inhibit TNF alpha induced programmed cell death or apoptosis . ^^^ |
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Interacting proteins: Q13489 and P19438 |
Pubmed |
SVM Score :0.0 |
Our data suggest that cIAP 2 may regulate the turnover of TRAF 1 by adding polyubiquitin chains on Lys 185 or Lys 193 following its recruitment to TNF R signaling complexes . . ^^^ |
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Interacting proteins: Q13489 and P19438 |
Pubmed |
SVM Score :0.0 |
NA |
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Interacting proteins: Q13489 and P19438 |
Pubmed |
SVM Score :0.0 |
NA |
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Interacting proteins: Q13489 and P19438 |
Pubmed |
SVM Score :0.0 |
NA |
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Interacting proteins: Q13489 and P19438 |
Pubmed |
SVM Score :0.0 |
NA |
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Interacting proteins: Q13489 and P19438 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: Q13489 and P19438 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: Q13489 and P19438 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: Q13489 and P19438 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: Q13489 and P19438 |
Pubmed |
SVM Score :0.0 |
NA |
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Interacting proteins: Q13489 and P19438 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: Q13489 and P19438 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: Q13489 and P19438 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: Q13489 and P19438 |
Pubmed |
SVM Score :0.0 |
NA |
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