| Interacting proteins: Q9H2S9 and Q13422 |
Pubmed |
SVM Score :0.0 |
| Eos : a novel member of the Ikaros gene family expressed predominantly in the developing nervous system . ^^^ Eos protein could interact with itself and Ikaros protein through its C terminal portion in the yeast two hybrid assay . ^^^ These findings suggested that Eos may have important roles in neural development similarly to the Ikaros family in the development of hemolymphoid tissue . . ^^^ |
|
| Interacting proteins: Q9H2S9 and Q13422 |
Pubmed |
SVM Score :0.0 |
| A PCR amplification strategy that is based on regions of shared sequence identity in Ikaros multigene family members found in mammals and several other vertebrates has led to the recovery of cDNAs that represent the orthologues of Ikaros , Aiolos , Helios , and Eos in Raja eglanteria ( clearnose skate ) , a cartilaginous fish that is representative of an early divergence event in the phylogenetic diversification of the vertebrates . ^^^ |
|
| Interacting proteins: Q9H2S9 and Q13422 |
Pubmed |
SVM Score :0.0 |
| Eos and pegasus , two members of the Ikaros family of proteins with distinct DNA binding activities . ^^^ Here we describe two additional Ikaros family proteins , Eos and Pegasus . ^^^ |
|
| Interacting proteins: Q9H2S9 and Q13422 |
Pubmed |
SVM Score :0.0 |
| The mammalian Ikaros like family of transcription factors consists of five members , Ikaros , Helios , Aiolos , Eos and Pegasus , of which the first three appear to be essential for lymphocyte development . ^^^ Phylogenetic analysis based on the alignable segments of the sequences does not identify the orthologous gene in jawed vertebrates but rather shows equidistance of the lamprey Ikaros like factors to each other and to Ikaros , Helios , Aiolos and Eos . ^^^ |
|
| Interacting proteins: Q9H2S9 and Q13422 |
Pubmed |
SVM Score :0.0 |
| Finally , we show that , barring CtBP , the Ikaros family members Aiolos , Helios , and Eos can associate with all of the identified corepressors of Ikaros including its newly identified interactors , Class 2 HDACs . . ^^^ |
|
| Interacting proteins: Q9H2S9 and Q13422 |
Pubmed |
SVM Score :0.0 |
| The Ikaros family protein Eos associates with C terminal binding protein corepressors . ^^^ Eos is a zinc finger transcription factor of the Ikaros family . ^^^ |
|
| Interacting proteins: Q9H2S9 and Q13422 |
Pubmed |
SVM Score :0.0 |
| Surprisingly , in contrast to the behavior exhibited by Ikaros , the C terminal domain of Eos inhibits the DNA binding activity of the full length protein . ^^^ |
|