| Interacting proteins: Q9HBI0 and Q13418 |
Pubmed |
SVM Score :0.96101614 |
| Like affixin , gamma parvin directly associates with ILK through its CH 2 domain and colocalizes with ILK at focal adhesions as well as the leading edge of PMA stimulated U 937 cells plated on fibronectin . 0.96101614^^^ Taken together with the results that gamma parvin could form a complex with some important cytoskeletal proteins , such as alphaPIX , alpha actinin , and paxillin as demonstrated for affixin and actopaxin ( alpha parvin ) , the results in this study suggest that the ILK gamma parvin complex is critically involved in the initial integrin signaling for leukocyte migration . . 0.69492515^^^ |
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| Interacting proteins: Q9HBI0 and Q13418 |
Pubmed |
SVM Score :0.0 |
| They consist of three members ( alpha , beta , and gamma parvin ) , form a functional complex with integrin linked kinase ( ILK ) and PINCH , and link integrins to the actin cytoskeleton . ^^^ Whereas alpha parvin is not expressed in hematopoietic cells , beta parvin is only found in myeloid cells and gamma parvin is present in both cells of the myeloid and lymphoid lineages , where it binds ILK . ^^^ |
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