| Fourthly , the association of ILK 1 with caveolin 1 regulated its cytoplasmic retention ; if it was not associated with caveolin 1 , it was transported to the nucleus . 0.68951708^^^ Firstly , by using a confocal microscopy and a transfection approach , we obtained the evidence that ILK 1 interacts physically with caveolin 1 , a 22 kDa integral membrane protein , which is the principal structural and regulatory component of caveolae membranes . 0.61126781^^^ In addition , we found that native ILK 1 is associated with endogenous caveolin 1 in COS 1 cells . 0.52702326^^^ |