Pubmed abstracts for Protein-Protein Interaction search result :


Interacting proteins: Q13418 and Q03135 Pubmed SVM Score :0.68951708
Fourthly , the association of ILK 1 with caveolin 1 regulated its cytoplasmic retention ; if it was not associated with caveolin 1 , it was transported to the nucleus . 0.68951708^^^ Firstly , by using a confocal microscopy and a transfection approach , we obtained the evidence that ILK 1 interacts physically with caveolin 1 , a 22 kDa integral membrane protein , which is the principal structural and regulatory component of caveolae membranes . 0.61126781^^^ In addition , we found that native ILK 1 is associated with endogenous caveolin 1 in COS 1 cells . 0.52702326^^^
Interacting proteins: Q13418 and Q03135 Pubmed SVM Score :0.0
Integrin linked kinase ( ILK ) and caveolin 1 ( cav 1 ) are implicated in the pathogenesis of cancer . ^^^ We examined whether ILK and cav 1 interact in SHEP human neuroblastoma cells because ILK is present in caveolae enriched membranes and contains a putative cav binding domain . ^^^ Control SHEP cells and ILK transfectants express high levels of ILK and cav 1 . ^^^ Immunoprecipitation with anti cav 1 co immunoprecipitates a 59 kDa protein that is immunoreactive with the anti ILK antibody , and this interaction is partially prevented in cells expressing ILK mutCavbd . ^^^ Cav 1 and ILK partially colocalize in SHEP cells , also supporting these data . ^^^