| Interacting proteins: Q9UBD5 and Q13416 |
Pubmed |
SVM Score :0.0 |
| Human and Drosophila LAT both associate with ORC 2 and are related to yeast ORC 3 , suggesting that LAT functions in DNA replication during cell proliferation . . ^^^ |
|
| Interacting proteins: Q9UBD5 and Q13416 |
Pubmed |
SVM Score :0.0 |
| Orc 2 , Orc 3 , and Orc 5 also are detected in non proliferating cells like cardiac myocytes , adrenal cortical cells , and neurons , suggesting an additional role of these proteins in non proliferating cells . ^^^ |
|
| Interacting proteins: Q9UBD5 and Q13416 |
Pubmed |
SVM Score :0.0 |
| We found that the C terminal region of ORC 2 interacts directly with the N terminal region of ORC 3 . ^^^ A fragment containing the N terminal 200 residues of ORC 3 ( ORC3N ) competitively inhibited the ORC 2 ORC3 interaction . ^^^ |
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| Interacting proteins: Q9UBD5 and Q13416 |
Pubmed |
SVM Score :0.0 |
| To define the physiological functions of the mammalian ORC , we cloned ORC subunit cDNAs from mouse NIH3T3 cells and found novel variant forms of Orc 1 , Orc 2 , and Orc 3 each derived from alternative RNA splicing . ^^^ Taken together , we conclude that mouse Orc 1 , Orc 2 , and Orc 3 each exist in two alternative splicing variants and that naturally occurring Orc1B lacks a functional domain that is essential for nuclear translocation and proteasome dependent degradation . . ^^^ |
|
| Interacting proteins: Q9UBD5 and Q13416 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9UBD5 and Q13416 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9UBD5 and Q13416 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9UBD5 and Q13416 |
Pubmed |
SVM Score :0.0 |
| NA |
|