| Interacting proteins: Q13393 and P11233 |
Pubmed |
SVM Score :0.8807024 |
| RalA was found to co localize with phospholipase D 1 ( PLD 1 ) at the plasma membrane in PC 12 cells . 0.8807024^^^ |
|
| Interacting proteins: Q13393 and P11233 |
Pubmed |
SVM Score :0.99207399 |
| PLD 1 has also been shown to be associated with the small GTPase RalA , which functions downstream from Ras in a Ras RalA GTPase cascade that facilitates intracellular signal transduction . 0.99207399^^^ Although PLD 1 associates directly with RalA , RalA has no effect upon the activity of PLD 1 . 0.66200369^^^ |
|
| Interacting proteins: Q13393 and P11233 |
Pubmed |
SVM Score :0.55510558 |
| The results suggest that the independent interactions of RalA and ARF 1 with PLD 1 are responsible for the synergistic activation . . 0.55510558^^^ |
|
| Interacting proteins: Q13393 and P11233 |
Pubmed |
SVM Score :0.0 |
| RalA interacts directly with the Arf responsive , PIP 2 dependent phospholipase D 1 . ^^^ |
|
| Interacting proteins: Q13393 and P11233 |
Pubmed |
SVM Score :0.0 |
| Ral activation of these responses is likely through an as yet uncharacterized effector pathway , as we find activation of NF kappaB and the cyclin D 1 promoter by Ral is independent of association of Ral with active phospholipase D 1 or Ral binding protein 1 , two proteins proposed to mediate Ral function in cells . . ^^^ |
|
| Interacting proteins: Q13393 and P11233 |
Pubmed |
SVM Score :0.0 |
| RalA , a small GTPase that functions as a downstream effector molecule of Ras , exists in a complex with PLD 1 . ^^^ These data demonstrate that either RalA or PLD 1 can cooperate with EGF receptor to transform cells . . ^^^ |
|
| Interacting proteins: Q13393 and P11233 |
Pubmed |
SVM Score :0.0 |
| We report here that EGF receptor endocytosis is dependent upon PLD and the PLD 1 regulators , protein kinase C alpha and RalA . ^^^ |
|
| Interacting proteins: Q13393 and P11233 |
Pubmed |
SVM Score :0.0 |
| Constitutive class 1 mGluR internalization is not dependent on the downstream Ral effector proteins Ral binding protein 1 and PLD 1 or either ADP ribosylation factors ARF 1 or ARF 6 . ^^^ |
|
| Interacting proteins: Q13393 and P11233 |
Pubmed |
SVM Score :0.0 |
| NA |
|